Catalog No.
Product Name
Application
Product Information
Citations
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Antidepressant
(1S,4S)-N-Desmethyl Sertraline hydrochloride is a metabolite of Sertraline, acting primarily as a selective serotonin reuptake inhibitor. This compound exhibits significant antidepressant activity, making it valuable in the study of depression and related disorders. It is utilized in research to investigate serotonin modulation and its effects on mood and behavior. -
Serotonin Reuptake Inhibitor
(S)-Norfluoxetine is a selective serotonin reuptake inhibitor that primarily targets the serotonin transporter. It has been shown to enhance allopregnanolone levels and decrease aggressive behavior in socially isolated murine models. This compound is valuable in research related to neuropharmacology and the understanding of mood and anxiety disorders. -
Nervous System Stimulant
3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant primarily by promoting the release of serotonin and dopamine. This compound exhibits notable effects on mood enhancement and increased energy levels, making it valuable for research into neuropharmacology and the study of stimulant effects on behavior. Its ability to modulate neurotransmitter activity positions it as a useful tool in investigating conditions related to mood disorders and attention. -
SERT Inhibitor
Nardosinonediol is a selective serotonin transporter (SERT) inhibitor. It demonstrates significant modulation of serotonin uptake, making it a valuable tool for studying serotonin-related pathways. This compound is primarily used in research focused on neuropharmacology, mood disorders, and the development of antidepressant therapies. -
Serotonin Reuptake Inhibitor
(Rac)-Dapoxetine hydrochloride is a racemic mixture of Dapoxetine hydrochloride, a selective serotonin reuptake inhibitor (SSRI) that primarily targets serotonin transporters. This compound exhibits notable efficacy in the treatment of premature ejaculation (PE) and is valuable in research aimed at understanding this condition. Its pharmacological profile positions it as a significant tool for studying serotonin-related pathways in human sexual health. -
Serotonin Transporter Control
N-Nitroso fluoxetine is a derivative of fluoxetine that acts as a selective serotonin reuptake inhibitor (SSRI). This compound primarily targets the serotonin transporter, modulating serotonin levels in the synaptic cleft and influencing mood regulation. N-Nitroso fluoxetine is utilized in antidepressant research, contributing to the understanding of serotonin modulation in psychiatric disorders. -
Serotonin Reuptake Inhibitor
DA-8031 is a selective serotonin reuptake inhibitor (SSRI) with oral bioavailability. It demonstrates the ability to modulate serotonin levels, making it a valuable compound for studying conditions related to serotonin dysregulation, particularly premature ejaculation (PE). This compound serves as an important tool for research into therapeutic interventions for PE and related disorders. -
Serotonin Reuptake Inhibitor
Lubazodone is a selective serotonin reuptake inhibitor (SSRI) that primarily targets the serotonin transporter. It exhibits significant antidepressant activity and is utilized in the investigation of various depressive disorders. Research applications include exploring its effects on mood regulation and neurochemical pathways associated with depression. -
Serotonin transporter inhibitor
Imipramine Hydrochloride is a tricyclic antidepressant. Inhibits the serotonin and norepinephrine transporters but has little effect on the dopamine transporter. -
noradrenalin transporters inhibitor
Desipramine hydrochloride is a tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (Ki values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).
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serotonin transporter (SER) inhibitor
Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT1A receptor partial agonist. -
serotonin uptake inhibitor
Paroxetine Mesylate is a serotonin uptake inhibitor that is effective in the treatment of depression. -
triple reuptake inhibitor
Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. -
triple reuptake inhibitor
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively. -
dual NE/DA transporter inhibitor
Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively. -
Serotonin reuptake inhibitor (SSRI)
Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with Ki of 0.89 nM. -
serotonin-norepinephrine reuptake inhibitor
Nitroxazepine is a tricyclic antidepressant (TCA) for the treatment of depression. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor. -
serotonin reuptake inhibitor
Azaphen is a potent inhibitor of the reuptake of serotonin.
