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Biological Activity
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt.
Targets
| HIV-1 (CEM-SS, H9, H9IIIB, U1 cells) | Akt (PC3 cells) | |||
| 20 nM | 130 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.22 mL | 156.1 mL | 312.2 mL |
| 0.5 mM | 6.24 mL | 31.22 mL | 62.44 mL |
| 1 mM | 3.12 mL | 15.61 mL | 31.22 mL |
| 5 mM | 0.62 mL | 3.12 mL | 6.24 mL |
*The above data is based on the productmolecular weight 320.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13210 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 35943-35-2 |
| Formula | C13H16N6O4 |
| M. Wt | 320.31 |
| Purity | >98% |
| Synonyms | NSC 154020, TCN, API-2 |
| SMILES | CN1C2=NC=NC3=C2C(=CN3[[email protected]]4[[email protected]@H]([[email protected]@H]([[email protected]](O4)CO)O)O)C(=N1)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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