Tubulin Inhibitor 14 targets NQO2 (quinone oxidoreductase 2) and exhibits a potent inhibitory effect with an IC50 of 1.0 μM. It disrupts tubulin polymerization and impedes the formation of capillary-like structures in endothelial cells. This microtubule-destabilizing agent possesses potential tumor-selectivity and exhibits antiangiogenic and vascular-disruptive properties, making it valuable for research in cancer biology and angiogenesis.
Tubulin Inhibitor 14 targets NQO2 (quinone oxidoreductase 2) and exhibits a potent inhibitory effect with an IC50 of 1.0 μM. It disrupts tubulin polymerization and impedes the formation of capillary-like structures in endothelial cells. This microtubule-destabilizing agent possesses potential tumor-selectivity and exhibits antiangiogenic and vascular-disruptive properties, making it valuable for research in cancer biology and angiogenesis.
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