Total item
Cart Subtotal
$0.00 Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9.
| In vitro (25°C) | DMSO | 69 mg/mL (176.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (5.12 mM) | ||
| In vivo | 1% CMC Na | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.61 mL | 128.07 mL | 256.13 mL |
| 0.5 mM | 5.12 mL | 25.61 mL | 51.23 mL |
| 1 mM | 2.56 mL | 12.81 mL | 25.61 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17861 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1616493-44-7 |
| Formula | C22H19FN4O2 |
| M. Wt | 390.42 |
| Purity | >98% |
| Synonyms | Tucidinostat; HBI-8000; HBI 8000; HBI8000 Chidamide; CS-055; CS 055; CS055 |
| SMILES | O=C(NC1=CC=C(F)C=C1N)C2=CC=C(CNC(/C=C/C3=CC=CN=C3)=O)C=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Tucidinostat (Chidamide) | Tucidinostat (Chidamide) Supplier | purchase | cost | manufacturer | order | distributor | buy 1616493-44-7| 1616493-44-7 Supplier | purchase 1616493-44-7 | 1616493-44-7 cost | 1616493-44-7 manufacturer | order 1616493-44-7 | 1616493-44-7 distributor
Adooq Quality Guarantee
We promise all products perform as described.