U0126 is a selective inhibitor of MEK1 and MEK2, functioning through a non-ATP competitive mechanism. It demonstrates potent biological activity with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. U0126 is utilized in research to investigate autophagy and mitophagy processes, providing insights into cellular signaling pathways and potential therapeutic targets in cancer and other diseases.
U0126 is a selective inhibitor of MEK1 and MEK2, functioning through a non-ATP competitive mechanism. It demonstrates potent biological activity with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. U0126 is utilized in research to investigate autophagy and mitophagy processes, providing insights into cellular signaling pathways and potential therapeutic targets in cancer and other diseases.
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