U7D-1

Name: U7D-1
Brand: Adooq Bioscience
SKU: A23953
Rating: 5 (288 reviews)

Catalog No.: A23953

USP7 PROTAC Degrader

U7D-1 is a first-in-class, potent, and selective PROTAC degrader of USP7 (ubiquitin-specific protease 7), with a DC₅₀ of 33 nM in RS4;11 cells. It exhibits anticancer activity and induces apoptosis in Jeko-1 cells, supporting its utility in cancer research targeting deubiquitinating enzymes.

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Grouped product items
Size	Price	Stock
1mg	$225.00	In stock
5mg	$675.00	In stock
10mg	$1,150.00	In stock
50mg	$3,450.00	In stock
Bulk Size	Bulk Discount

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Research use only. We do not sell to patients.

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Biological Activity

Description	U7D-1 is a first-in-class, potent, and selective PROTAC degrader of USP7 (ubiquitin-specific protease 7), with a DC₅₀ of 33 nM in RS4;11 cells. It exhibits anticancer activity and induces apoptosis in Jeko-1 cells, supporting its utility in cancer research targeting deubiquitinating enzymes.

Product Information

Catalog Num	A23953
Formula	C53H65N9O7
Molecular Weight	940.14
CAS Number	nan
SMILES	O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCCCCCNCC4=CC=C(C5=C(C6=NN5C)N=CN(CC7(O)CCN(C(C[C@H](C8=CC=CC=C8)C)=O)CC7)C6=O)C=C4)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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