VUF11207

Catalog No.: A12869
CXCR Agonist
VUF11207 is a potent agonist of the CXCR7 receptor, demonstrating a high affinity with a pKi of 8.1. This compound effectively induces the recruitment of β-arrestin2, with an pEC50 value of 8.8, and promotes the subsequent internalization of CXCR7, with an pEC50 of 7.9. VUF11207 is valuable for research applications focused on CXCR signaling pathways and β-arrestin-mediated processes.
Grouped product items
Size Price Stock Qty
5mg
$60.00
In stock
10mg
$100.00
In stock
25mg
$195.00
In stock
50mg
$305.00
In stock
100mg
$480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVUF11207 is a potent agonist of the CXCR7 receptor, demonstrating a high affinity with a pKi of 8.1. This compound effectively induces the recruitment of β-arrestin2, with an pEC50 value of 8.8, and promotes the subsequent internalization of CXCR7, with an pEC50 of 7.9. VUF11207 is valuable for research applications focused on CXCR signaling pathways and β-arrestin-mediated processes.
Product Information
Catalog NumA12869
FormulaC27H35FN2O4
Molecular Weight470.58
CAS Number1378524-41-4
SMILESCN(CCC1)C1CCN(C/C(C)=C/C2=C(C=CC=C2)F)C(C3=CC(OC)=C(C(OC)=C3)OC)=O
Useful Calculator

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