WZ811

Catalog No.: A12588

CXCR4 antagonist

WZ811

WZ811 Chemical Structure

CAS NO. 55778-02-4

WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$140.00
50 mg
$225.00
100 mg
$315.00
10mM * 1mL in DMSO
$59.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).
Targets
CXCR4
0.3 nM(EC50)
In vitro DMSO 30 mg/mL (103.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.44 mL 172.2 mL 344.4 mL
0.5 mM 6.89 mL 34.44 mL 68.88 mL
1 mM 3.44 mL 17.22 mL 34.44 mL
5 mM 0.69 mL 3.44 mL 6.89 mL

*The above data is based on the productmolecular weight 290.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12588
Actions Antagonist
M. Wt 290.36
Formula 0
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 55778-02-4
Synonyms WZ811; WZ-811; WZ 811.
SMILES C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3

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