Dexamethasone

Catalog No.: A10299

glucocorticoid receptor agonist

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant. Its potency is about 20-30 times that of the naturally occurring hormone hydrocortisone and 4-5 times of prednisone.
Grouped product items
Product Name Price Stock Qty
Dexamethasone 500mg
$45.00
In stock
Dexamethasone 10mM * 1mL in DMSO
$60.00
In stock
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Adooq Products cited in reputable paper
Adooq's Dexamethasone has been cited by 2 publications
  • Ken Kobayashi, .et al. , Cell Tissue Res, 2022, Sep;389(3):501-515 PMID: 35748981
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Biological Activity
    Discription Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs. It acts as an anti-inflammatory and immunosuppressant. Its potency is about 20-30 times that of the naturally occurring hormone hydrocortisone and 4-5 times of prednisone.
    Product Information
    Catalog Num A10299
    Formula C22H29FO5
    Molecular Weight 392.5
    CAS Number 50-02-2
    SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
    Synonyms Decadron
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 73 mg/mL (186 mM)
    Water Insoluble
    Ethanol 6 mg/mL (15.28 mM)
    In vivo 5% DMSO+45% PEG 300+H2O 12 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.48 mL 127.39 mL 254.78 mL
    0.5 mM 5.1 mL 25.48 mL 50.96 mL
    1 mM 2.55 mL 12.74 mL 25.48 mL
    5 mM 0.51 mL 2.55 mL 5.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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