Fludarabine Phosphate (Fludara)

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Catalog No. A10395

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Fludarabine Phosphate 10mg A10395-10

Regular Price: $40.00

Special Price: $32.00

Fludarabine Phosphate 50mg A10395-50

Regular Price: $140.00

Special Price: $112.00

Fludarabine Phosphate 100mg A10395-100

Regular Price: $260.00

Special Price: $208.00

Fludarabine Phosphate 10mM * 1mL in DMSO A10395-10mM-D

Regular Price: $74.00

Special Price: $59.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.

Fludarabine Phosphate (Fludara)

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Chemical Information

Catalog Num A10395
Actions No
M. Wt 365.2
Formula C10H13FN5O7P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75607-67-9
Synonyms N/A
SMILES code O[[email protected]]1[[email protected]](O)[[email protected]](O[[email protected]]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O
Chemical Name 9-bata-D-Arabinofuranosyl-2-fluoroadenine phosphate

Biological Activity

Description
Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.
Targets
DNA polymerase α DNA polymerase δ
1.1 μM(Ki )1.3 μM(Ki)

Solubility

Solubility (25°C) * In vitro DMSO 73 mg/mL (199.88 mM)
Water 2 mg/mL heating (5.47 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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