MK-2206 2HCl

Catalog No.: A10003
AKT Inhibitor
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.
Grouped product items
Product Name Price Stock Qty
MK-2206 5mg
$60.00
In stock
MK-2206 10mg
$72.00
In stock
MK-2206 25mg
$115.00
In stock
MK-2206 50mg
$162.00
In stock
MK-2206 2HCl 10mM * 1mL in DMSO
$80.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's MK-2206 2HCl has been cited by 19 publications
  • Yi-Ru Pan, .et al. , Int J Biol Sci, 2023, May 21;19(9):2772-2786 PMID: 37324940
  • Giorgio Caratti, .et al. , EMBO Rep, 2023, Feb 6;24(2):e55363 PMID: 36520372
  • Ming-Chun Hung, .et al. , Cell Biosci, 2022, 12: 122 PMID: 35918763
  • Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890
  • Majid Momeny, .et al. , Life Sci, 2021, Dec 15;287:120100 PMID: 34715143
  • Ali Nasrollahzadeh, .et al. , Biochim Biophys Acta Mol Cell Res, 2021, Jun 26;1868(10):119087 PMID: 34182011
  • Rona Aviram, .et al. , PLoS Biol, 2021, Dec 30;19(12):e3001492 PMID: 34968386
  • Cristina Roselló-Busquets, .et al. , Front Mol Neurosci, 2020, 13: 56 PMID: 32317932
  • Dai-Chi Liu, .et al. , eNeuro, 2020, Mar 27;7(2):ENEURO.0438-19.2020 PMID: 32161037
  • Nishihama K, .et al. , Metabolism, 2018, May;82:88-99 PMID: 29366755
  • J Wei, .et al. , bioRxiv, 2018, 2018
  • Joo Sang Lee, .et al. , Nat Commun, 2018, 9: 2546 PMID: 29959327
  • Wan-Ting Hu, .et al. , Am J Cancer Res, 2018, 8(9): 1739-1751 PMID: 30323967
  • Angela M. Gocher, .et al. , J Biol Chem, 2017, Aug 25; 292(34): 14188-14204 PMID: 28634229
  • Kusuyama J, .et al. , Biochem J, 2017, Oct 5;474(20):3421-3437 PMID: 28887384
  • Pi-Lin Sung, .et al. , Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408
  • Mikaël M. Martino, .et al. , Nat Commun, 2016, 7: 11051 PMID: 27001940
  • Dominik Schulz, .et al. , Am J Cancer Res, 2016, 6(9): 1963-1975 PMID: 27725902
  • Jewett KA, .et al. , J Neurochem., 2015, Oct;135(2):226-33 PMID: 26250624
  • Biological Activity
    Discription MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A10003
    Formula C25H21N5O.2HCl
    Molecular Weight 480.4
    CAS Number 1032350-13-2
    SMILES C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 12 mg/mL (24.98 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5%Tween80+ 50%H2O 0.59 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.82 mL 104.08 mL 208.16 mL
    0.5 mM 4.16 mL 20.82 mL 41.63 mL
    1 mM 2.08 mL 10.41 mL 20.82 mL
    5 mM 0.42 mL 2.08 mL 4.16 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy MK-2206 2HCl | MK-2206 2HCl Supplier | purchase MK-2206 2HCl | MK-2206 2HCl cost | MK-2206 2HCl manufacturer | order MK-2206 2HCl | MK-2206 2HCl distributor | buy 1032350-13-2 | 1032350-13-2 Supplier | purchase 1032350-13-2 | 1032350-13-2 cost | 1032350-13-2 manufacturer | order 1032350-13-2 | 1032350-13-2 distributor