MK-2206 2HCl

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AKT Inhibitor

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Catalog No. A10003

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK-2206 5mg A10003-5

Regular Price: $60.00

Special Price: $51.00

MK-2206 10mg A10003-10

Regular Price: $100.00

Special Price: $85.00

MK-2206 25mg A10003-25

Regular Price: $150.00

Special Price: $127.50

MK-2206 50mg A10003-50

Regular Price: $250.00

Special Price: $212.50

MK-2206 2HCl 10mM * 1mL in DMSO A10003-10mM-D
$117.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.

MK-2206 2HCl

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Chemical Information

Catalog Num A10003
Actions Inhibitor
M. Wt 480.4
Formula C25H21N5O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1032350-13-2
Synonyms MK2206
SMILES code C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Chemical Name 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

Biological Activity

Description
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.
Targets
Akt1 (Cell-free assay) Akt2 (Cell-free assay) Akt3 (Cell-free assay)
8 nM12 nM65 nM

Solubility

Solubility (25°C) * In vitro DMSO 14 mg/mL (29.14 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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