10'-Desmethoxystreptonigrin is an antibiotic that acts as an inhibitor of Ras Farnesyltransferase, exhibiting an IC50 of 21 μM. This compound demonstrates broad-spectrum antibacterial activity and shows antitumor effects against P388 leukemia, with an LD50 of 8.8 mg/kg indicating minimal cytotoxicity. It is a valuable reagent for research applications targeting antibiotic resistance and cancer therapeutics.
10'-Desmethoxystreptonigrin is an antibiotic that acts as an inhibitor of Ras Farnesyltransferase, exhibiting an IC50 of 21 μM. This compound demonstrates broad-spectrum antibacterial activity and shows antitumor effects against P388 leukemia, with an LD50 of 8.8 mg/kg indicating minimal cytotoxicity. It is a valuable reagent for research applications targeting antibiotic resistance and cancer therapeutics.
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