Signaling Pathway
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| Discription | AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors. | ||
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| Catalog Num | A12464 |
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| Formula | C17H16ClN3O |
| Molecular Weight | 313.78 |
| CAS Number | 1056901-62-2 |
| SMILES | C1=CC(=CC=C1C2=CNN=C2)[C@@](CN)(C3=CC=C(C=C3)Cl)O |
| Synonyms | AT 13148, AT-13148 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 55 mg/mL (175.28 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.87 mL | 159.35 mL | 318.69 mL |
| 0.5 mM | 6.37 mL | 31.87 mL | 63.74 mL |
| 1 mM | 3.19 mL | 15.93 mL | 31.87 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.37 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
