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pan-Pim kinase inhibitor

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Catalog No. A13203

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AZD1208 5mg A13203-5

Regular Price: €66.50

Special Price: €59.85

AZD1208 10mg A13203-10

Regular Price: €95.00

Special Price: €85.50

AZD1208 25mg A13203-25

Regular Price: €190.00

Special Price: €171.00

AZD1208 50mg A13203-50

Regular Price: €332.50

Special Price: €299.25

AZD1208 10mM * 1mL in DMSO A13203-10mM-D

Regular Price: €71.25

Special Price: €64.13

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.


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Publications citing Adooq Products
AZD1208 Citations (5)
  • Remy J, .et al. Inhibition of PIM1 blocks the autophagic flux to sensitize glioblastoma cells to ABT-737-induced apoptosis, Biochim Biophys Acta Mol Cell Res, 2019, Feb;1866(2):175-189 PMID: 30389373
  • Andrea L. Casillas, .et al. Hypoxia-inducible PIM kinase expression promotes resistance to anti-angiogenic agents, Clin Cancer Res, 2018, Jan 1; 24(1): 169-180 PMID: 29084916
  • Jin H. Song, .et al. Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase, Mol Cancer Ther, 2018, Dec;17(12):2710-2721 PMID: 30190422
  • Sathish K.R. Padi, .et al. Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset, Oncotarget, 2017, May 2; 8(18): 30199-30216 PMID: 28415816
  • Lim R, .et al. Inhibition of PIM1 kinase attenuates inflammation-induced pro-labour mediators in human foetal membranes in vitro, Mol Hum Reprod, 2017, Jun 1;23(6):428-440 PMID: 28333279

Chemical Information

Catalog Num A13203
Actions Inhibitor
M. Wt 379.48
Formula C21H21N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1204144-28-4
Synonyms AZD 1208, AZD-1208
SMILES C1C[[email protected]](CN(C1)C2=C(C=CC=C2/C=C\3/C(=O)NC(=O)S3)C4=CC=CC=C4)N

Biological Activity

AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity.
Pim1 (Cell-free assay) Pim3 (Cell-free assay) Pim2 (Cell-free assay)
0.4 nM1.9 nM5 nM


Solubility (25°C)* In vitro DMSO 75 mg/mL heating (197.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.35 mL 131.76 mL 263.52mL
0.5 mM 5.27 mL 26.35 mL 52.7 mL
1 mM 2.64 mL 13.18 mL 26.35 mL
5 mM 0.53 mL 2.64 mL 5.27 mL

*The above data is based on the productmolecular weight 379.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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