BCN-​exo-​PEG3-​NH2

Catalog No.: A81790
PROTAC Linker
BCN-exo-PEG3-NH2 is a PEG-based linker designed for PROTAC (PROteolysis-TArgeting Chimeras) synthesis. This compound features a BCN (bicyclononyne) group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its unique properties make it suitable for applications in targeted protein degradation research, enabling precise modulation of protein levels within biological systems.
Grouped product items
Size Price Stock Qty
50mg
$190.00
In stock
100mg
$310.00
In stock
250mg
$575.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBCN-exo-PEG3-NH2 is a PEG-based linker designed for PROTAC (PROteolysis-TArgeting Chimeras) synthesis. This compound features a BCN (bicyclononyne) group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its unique properties make it suitable for applications in targeted protein degradation research, enabling precise modulation of protein levels within biological systems.
Product Information
Catalog NumA81790
FormulaC19H32N2O5
Molecular Weight368.47
CAS Number1841134-72-2
SMILESNCCOCCOCCOCCNC(OC[C@@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
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