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(E/Z)-BIBW2992 (E/Z-Afatinib)

Catalog No.: A10141
EGFR inhibitor
Adooq's (E/Z)-BIBW2992 (E/Z-Afatinib) has been cited by 6 publications
BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
(E/Z)-BIBW2992 (E/Z-Afatinib)
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Size Price Stock Qty
100mg
$20.00
In stock
200mg
$30.00
In stock
500mg
$40.00
In stock
1g
$55.00
In stock
10mM * 1mL in DMSO
$20.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Other Forms of (E/Z)-BIBW2992 (E/Z-Afatinib)

Adooq Products cited in reputable paper
Adooq's (E/Z)-BIBW2992 (E/Z-Afatinib) has been cited by 6 publications
  • Song Han, .et al. , Neoplasia, 2025, Jan:59:101070 PMID: 39541736
  • Sang-Hyun Lee, .et al. , NPJ Precis Oncol, 2024, May 21;8(1):111 PMID: 38773241
  • Yi-Ru Pan, .et al. , Int J Biol Sci, 2023, May 21;19(9):2772-2786 PMID: 37324940
  • Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812
  • Van Sebille YZ, .et al. , Exp Biol Med (Maywood), 2019, Jun 11:1535370219855334 PMID: 31184924
  • Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358
    • Biological Activity
    Discription BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10141
    Formula C24H25ClFN5O3
    Molecular Weight 485.9
    CAS Number 439081-18-2
    SMILES CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4
    Synonyms Tomtovok
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Protein Tyrosine Kinases > EGFR/HER2
    Angiogenesis > EGFR/HER2
    JAK/Stat > EGFR/HER2
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