BX471

Catalog No.: A14409

CCR1 antagonist

BX471 Chemical Structure

CAS NO. 217645-70-0

BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $80.00

Special Price $64.00

10 mg

Regular Price: $150.00

Special Price $120.00

25 mg

Regular Price: $300.00

Special Price $240.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.99 mL 114.97 mL 229.94 mL
0.5 mM 4.6 mL 22.99 mL 45.99 mL
1 mM 2.3 mL 11.5 mL 22.99 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14409
Actions Antagonist
M. Wt 434.89
Formula C21H24ClFN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 217645-70-0
Synonyms BX-471, BX 471
SMILES CC1CN(CCN1C(=O)COC2=C(C=C(C=C2)Cl)NC(=O)N)CC3=CC=C(C=C3)F

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