CA-074 Methyl Ester

Catalog No.: A13593
Cathepsin B inhibitor
CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.
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Product Name Price Stock Qty
CA-074 Methyl Ester 5mg
Special Price $96.00 Regular Price $120.00
In stock
CA-074 Methyl Ester 10mg
Special Price $160.00 Regular Price $200.00
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CA-074 Methyl Ester 25mg
Special Price $320.00 Regular Price $400.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's CA-074 Methyl Ester has been cited by 4 publications
  • Qian Chu, .et al. , Food Chem Toxicol, 2021, Jan;147:111867 PMID: 33217525
  • Ye Tao, .et al. , Chemosphere, 2020, Mar;242:124959 PMID: 31669990
  • Ming Sun, .et al. , J Agric Food Chem, 2018, Nov 21;66(46):12376-12384 PMID: 30392375
  • Xueyan Wu, .et al. , Food Chem Toxicol, 2017, Aug;106(Pt A):273-282 PMID: 28579546
  • Biological Activity
    Discription CA-074 methyl ester is a cell-permeable analog of CA-074 that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.
    Product Information
    Catalog Num A13593
    Formula C19H31N3O6
    Molecular Weight 397.5
    CAS Number 147859-80-1
    SMILES CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC
    Synonyms CA-074 Me
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 77 mg/mL (193.72 mM)
    Water 77 mg/mL (193.72 mM)
    Ethanol 6 mg/mL (15.09 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.16 mL 125.79 mL 251.57 mL
    0.5 mM 5.03 mL 25.16 mL 50.31 mL
    1 mM 2.52 mL 12.58 mL 25.16 mL
    5 mM 0.5 mL 2.52 mL 5.03 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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