Metabolism - STK

ML-281 is a potent ans selective STK33 inhibitor with IC50 value of 14 nM.

ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor. ZT-12-037-01 effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vitro and in vivo.

STK16-IN-1 is a STK16 kinase inhibitor with an IC50 of 295 nM.