ZT-12-037-01

Catalog No.: A18395

ATP-competitive STK19 inhibitor

ZT-12-037-01

ZT-12-037-01 Chemical Structure

CAS NO. 2328073-61-4

ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor. ZT-12-037-01 effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vitro and in vivo.

Availability: In stock

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5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $120.00

Special Price $96.00

50 mg

Regular Price: $520.00

Special Price $416.00

100 mg

Regular Price: $920.00

Special Price $736.00

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Biological Activity

ZT-12-037-01 is a potent, selective, ATP-competitive STK19 inhibitor. ZT-12-037-01 effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vitro and in vivo.
In vitro DMSO 40 mg/mL (103.76 mM)
Water Insoluble
Ethanol 3 mg/mL (7.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.94 mL 129.7 mL 259.4 mL
0.5 mM 5.19 mL 25.94 mL 51.88 mL
1 mM 2.59 mL 12.97 mL 25.94 mL
5 mM 0.52 mL 2.59 mL 5.19 mL

*The above data is based on the productmolecular weight 385.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18395
Actions Inhibitor
CAS No. 2328073-61-4
Formula C21H31N5O2
M. Wt 385.51
Purity >98%
Synonyms ZT-12-037-01; ZT-12-03701; ZT-12-037 01; ZT-12037-01; ZT-1203701; ZT-12037 01; ZT-1203701; ZT-1203701; ZT-1203701;
SMILES COC1=CC2=NC(NC3CC3)=NC(NC4CCN(C(C)C)CC4)=C2C=C1OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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