CM-675

Catalog No.: A18741

PDE5/HDAC-1 inhibitor

CM-675

CM-675 Chemical Structure

CAS NO. 1872466-47-1

CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer??s disease.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 has potential to treat Alzheimer??s disease.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.64 mL 93.18 mL 186.35 mL
0.5 mM 3.73 mL 18.64 mL 37.27 mL
1 mM 1.86 mL 9.32 mL 18.64 mL
5 mM 0.37 mL 1.86 mL 3.73 mL

*The above data is based on the productmolecular weight 536.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18741
Actions Inhibitor
M. Wt 536.62
Formula C??H32N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1872466-47-1
Synonyms CM675, CM 675
SMILES O=C(NC1=CC=CC=C1N)C2=CC=C(CC3=CC=C(OCC)C(C4=NC5=C(N(C)N=C5CCC)C(N4)=O)=C3)C=C2

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