Cyclamidomycin is an acrylamide antibiotic that primarily targets nucleoside diphosphate kinase and pyruvate kinase in Escherichia coli, along with impairing oxidative phosphorylation in rat liver mitochondria. It exhibits broad-spectrum antibacterial activity against various bacteria, including Staphylococcus aureus, Micrococcus flavus, Staphylococcus lutea, Bacillus subtilis, Escherichia coli, Shigella flexneri, Salmonella typhosa, Proteus vulgaris, and Klebsiella pneumoniae, with minimum inhibitory concentrations ranging from 3.12 to 25 mg/ml. This compound is valuable for research on bacterial infections and mitochondrial function.
Cyclamidomycin is an acrylamide antibiotic that primarily targets nucleoside diphosphate kinase and pyruvate kinase in Escherichia coli, along with impairing oxidative phosphorylation in rat liver mitochondria. It exhibits broad-spectrum antibacterial activity against various bacteria, including Staphylococcus aureus, Micrococcus flavus, Staphylococcus lutea, Bacillus subtilis, Escherichia coli, Shigella flexneri, Salmonella typhosa, Proteus vulgaris, and Klebsiella pneumoniae, with minimum inhibitory concentrations ranging from 3.12 to 25 mg/ml. This compound is valuable for research on bacterial infections and mitochondrial function.
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