DBCO-​C6-​acid

Catalog No.: A42737
ADC Linker
DBCO-C6-acid is a non-cleavable ADC linker that facilitates the formation of antibody-drug conjugates (ADCs). Its unique DBCO moiety allows for efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is particularly useful in the synthesis of carmaphycin analogues, enabling targeted delivery of therapeutic agents for enhanced efficacy in research applications related to targeted cancer therapies.
Grouped product items
Size Price Stock Qty
50mg
$65.00
In stock
100mg
$95.00
In stock
250mg
$115.00
In stock
1g
$450.00
In stock
5g
$1,405.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-C6-acid is a non-cleavable ADC linker that facilitates the formation of antibody-drug conjugates (ADCs). Its unique DBCO moiety allows for efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is particularly useful in the synthesis of carmaphycin analogues, enabling targeted delivery of therapeutic agents for enhanced efficacy in research applications related to targeted cancer therapies.
Product Information
Catalog NumA42737
FormulaC21H19NO3
Molecular Weight333.38
CAS Number1425485-72-8
SMILESO=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2