DBCO-NHCO-PEG2-Biotin is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a DBCO (dibenzylcyclooctyne) group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its biotin component enhances the attachment of PROTACs to target proteins, facilitating studies on targeted protein degradation and cellular dynamics. DBCO-NHCO-PEG2-Biotin is essential for research applications involving targeted therapeutic strategies and the exploration of protein interactions.
DBCO-NHCO-PEG2-Biotin is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features a DBCO (dibenzylcyclooctyne) group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its biotin component enhances the attachment of PROTACs to target proteins, facilitating studies on targeted protein degradation and cellular dynamics. DBCO-NHCO-PEG2-Biotin is essential for research applications involving targeted therapeutic strategies and the exploration of protein interactions.
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