DBCO-PEG12-Maleimide is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules, enabling efficient and selective conjugation. This chemical reagent is valuable in targeted protein degradation studies and the development of novel therapeutic strategies.
DBCO-PEG12-Maleimide is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It features a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules, enabling efficient and selective conjugation. This chemical reagent is valuable in targeted protein degradation studies and the development of novel therapeutic strategies.
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