DBCO-PEG4-triethoxysilane

Catalog No.: A82693
PROTAC Linkers
DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker specifically designed for the synthesis of PROTACs. Its DBCO group facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. This compound is instrumental in the development of targeted protein degradation strategies, enhancing research in cancer therapy and other therapeutic areas.
Grouped product items
Size Price Stock Qty
5mg
$245.00
In stock
10mg
$405.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker specifically designed for the synthesis of PROTACs. Its DBCO group facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling efficient conjugation. This compound is instrumental in the development of targeted protein degradation strategies, enhancing research in cancer therapy and other therapeutic areas.
Product Information
Catalog NumA82693
FormulaC39H57N3O10Si
Molecular Weight755.97
CAS Number2353410-02-1
SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCC(NCCC[Si](OCC)(OCC)OCC)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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