DBCO-PEG5-DBCO

Catalog No.: A82163
PROTAC Linkers
DBCO-PEG5-DBCO is a PEG-based linker specifically designed for synthesizing PROTACs. Featuring a dibenzocyclooctyne (DBCO) moiety, this reagent enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its versatility makes it an invaluable tool in the development of targeted protein degradation strategies, facilitating research into novel therapeutic approaches in various biological systems.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-PEG5-DBCO is a PEG-based linker specifically designed for synthesizing PROTACs. Featuring a dibenzocyclooctyne (DBCO) moiety, this reagent enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules. Its versatility makes it an invaluable tool in the development of targeted protein degradation strategies, facilitating research into novel therapeutic approaches in various biological systems.
Product Information
Catalog NumA82163
FormulaC50H54N4O9
Molecular Weight854.99
CAS Number2363130-04-3
SMILESO=C(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)CCOCCOCCOCCOCCOCCC(NCCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O
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