DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies.
DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies.
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