Diclofenac sodium

Catalog No.: A10304

COX inhibitor

Diclofenac sodium

Diclofenac sodium Chemical Structure

CAS NO. 15307-79-6

Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.

Availability: In stock

Package Price Qty
25 mg
$70.00
50 mg
$120.00
100 mg
$200.00
200 mg
$350.00
10mM * 1mL in DMSO
$68.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.
Targets
COX-1 COX-2
60 nM200 nM
In vitro DMSO 64 mg/mL (201.17 mM)
Water 14 mg/mL (44 mM)
Ethanol 64 mg/mL (201.17 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.43 mL 157.17 mL 314.34 mL
0.5 mM 6.29 mL 31.43 mL 62.87 mL
1 mM 3.14 mL 15.72 mL 31.43 mL
5 mM 0.63 mL 3.14 mL 6.29 mL

*The above data is based on the productmolecular weight 318.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10304
Actions Inhibitor
M. Wt 318.13
Formula C14H10Cl2NNaO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15307-79-6
Synonyms N/A
SMILES C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+]

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