Diclofenac

Catalog No.: A17814

COX inhibitor

Diclofenac

Diclofenac Chemical Structure

CAS NO. 15307-86-5

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.

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500 mg

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Biological Activity

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.
In vitro DMSO 54 mg/mL (182.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.77 mL 168.83 mL 337.67 mL
0.5 mM 6.75 mL 33.77 mL 67.53 mL
1 mM 3.38 mL 16.88 mL 33.77 mL
5 mM 0.68 mL 3.38 mL 6.75 mL

*The above data is based on the productmolecular weight 296.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17814
Actions Inhibitor
CAS No. 15307-86-5
Formula C14H11Cl2NO2
M. Wt 296.15
Purity >98%
SMILES O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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