Diclofenac

Catalog No.: A17814

COX inhibitor

Diclofenac

Diclofenac Chemical Structure

CAS NO. 15307-86-5

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.

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500 mg
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Biological Activity

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.77 mL 168.83 mL 337.67 mL
0.5 mM 6.75 mL 33.77 mL 67.53 mL
1 mM 3.38 mL 16.88 mL 33.77 mL
5 mM 0.68 mL 3.38 mL 6.75 mL

*The above data is based on the productmolecular weight 296.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17814
Actions Inhibitor
M. Wt 296.15
Formula C14H11Cl2NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15307-86-5
SMILES O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl

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