Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
N2-iso-Butyroyl-3'-deoxy-3'-fluoro guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for research applications focused on cancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
(2',3',5'-Tri-O-acetyl)uridine 5-carboxylic acid is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies exploring therapeutic strategies and the biochemical pathways associated with nucleoside metabolism. -
Purine Nucleoside Analog
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, contributing to its efficacy in cancer research. The anticancer mechanisms include the inhibition of DNA replication and the induction of apoptosis, making it a valuable reagent for studying therapeutic strategies in oncology. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine acts as a purine nucleoside analog with significant anticancer properties. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’-O-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. Its unique structural modifications enhance its potential in studying purine metabolism and the mechanisms of action in cancer treatments. -
Purine Nucleoside Analog
3′-Bromo-3′-deoxythymidine is a purine nucleoside analog that exhibits significant antitumor activity primarily through the inhibition of DNA synthesis. This compound is effective against indolent lymphoid malignancies, contributing to apoptosis induction and disrupting cellular proliferation. It serves as a valuable tool in cancer research, particularly for exploring therapeutic strategies targeting nucleoside metabolism and DNA replication processes. -
Nucleoside Analogue
8-Azakinetin riboside is a nucleoside analogue that exhibits cytotoxic activity. It is structurally related to kinetin riboside, making it a valuable compound for research investigating the effects of nucleoside analogues on cellular pathways. This reagent is applicable in studies focused on cancer biology and the modulation of cellular growth and death. -
Cytidine Analog
2'-Deoxy-5'-O-DMT-5-methylcytidine is a cytidine analog that functions as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor properties, making it a valuable tool for cancer research and studies involving epigenetic modulation. Its unique structure allows for exploration of the regulatory mechanisms of methylation in cellular processes. -
Adenosine Analog
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-3'-O-DMT-adenosine is an adenosine analog that primarily targets adenosine receptors. It exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. This compound is valuable for research applications focusing on vascular biology, oncology, and the investigation of adenosine signaling pathways. -
Nucleoside Metabolite
Dixanthosine tetraphosphate is a nucleoside metabolite that plays a critical role in cellular signaling pathways. This compound is primarily involved in the regulation of nucleotide metabolism and can influence various cellular processes, making it valuable for research in cell biology and biochemistry. Its distinct structure also facilitates studies on phosphoribosyltransferase activity and nucleoside triphosphate synthesis. -
Cytidine Analog
2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog that functions as an inhibitor of DNA methyltransferases. Its mechanism of action involves modulating DNA methylation, which can lead to alterations in gene expression. This compound demonstrates potential anti-metabolic and anti-tumor activities, making it a valuable tool for cancer research and epigenetic studies. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[5-(propyn-1-yl)pyridin-3-yl]purine is a purine nucleoside analog exhibiting broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it valuable in cancer research. Additionally, this compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), facilitating advanced conjugation studies in chemical biology. -
Purine Nucleoside Analog
N6-Ethyl-2’-O-methyladenosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. This compound is valuable for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
5′-Amino-2′,5′-dideoxyuridine is a purine nucleoside analog with significant antitumor activity. It primarily exerts its effects through the inhibition of DNA synthesis and the induction of apoptosis, making it beneficial for research on indolent lymphoid malignancies. This compound is valuable for studies focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog that exerts its antitumor effects by inhibiting DNA synthesis and inducing apoptosis. This compound is particularly effective against indolent lymphoid malignancies, making it a valuable tool for cancer research. Its ability to mimic natural nucleosides positions it as a key candidate in the development of novel therapeutic strategies against various malignancies. -
Purine Nucleoside Analog
1-(3-Beta-amino-2,3-dideoxy-beta-d-threopenta-furanosyl)thymine is a purine nucleoside analog with significant biological activity against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research, offering insights into therapeutic strategies targeting nucleoside metabolism and tumor cell proliferation. -
Purine Nucleoside Analog
4-Deoxy-3’-β-C-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for investigations into therapeutic strategies targeting nucleoside metabolism and studying the molecular pathways involved in lymphoid malignancy treatments. -
Adenosine Analog
N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenosine analog known for its smooth muscle vasodilatory effects. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for research in oncology and cardiovascular studies. Its biological activity positions it as a key reagent for investigating adenosine receptor pathways and their implications in various therapeutic contexts. -
Nucleoside Metabolite
4-Hydroxyphenylacetylglutamic acid is a nucleoside metabolite derived from Morus alba L. This compound may play significant roles in biochemical pathways and offers insights into metabolic processes associated with plant-derived substances. Its research applications include studying nucleoside metabolism, investigating physiological effects in various biological systems, and exploring potential therapeutic avenues in cellular biology. -
Purine Nucleoside Analog
5-Hydroxymethyl-2’-O-(2-methoxyethyl)uridine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA replication and the induction of apoptosis. It is a valuable tool for researchers investigating cancer biology and therapeutic strategies in hematological contexts. -
Adenosine Analog
3’-O-t-Butyldimethylsilyladenosine is an adenosine analog known for its role as a smooth muscle vasodilator. This compound exhibits significant biological activity by influencing adenosine pathways, and it has also demonstrated potential in inhibiting cancer progression. Research applications include studies focused on cardiovascular response and cancer biology, making it a valuable tool in the exploration of therapeutic interventions. -
Adenosine Analog
2-(2,4-Dichlorobenzyl)thioadenosine is an adenosine analog that primarily functions as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it a valuable tool in cancer research. Its unique structural modifications may enhance the pharmacological properties compared to natural adenosine, facilitating further studies in both cardiovascular and oncological applications. -
Purine Nucleoside Analog
5-(Aminomethyl)-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in studies focusing on therapeutic strategies and molecular mechanisms underlying tumorigenesis. -
Purine Nucleoside Analog
2′,3′-Dideoxy-3′-fluoro-5-methylcytidine is a purine nucleoside analog that exerts significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound can be utilized in studies focused on the modulation of nucleoside metabolism and the exploration of therapeutic strategies for lymphoid tumors. -
Purine Nucleoside Analog
N2,N2-Dimethylamino-6-deamino adenosine is a purine nucleoside analog known for its potential anticancer properties. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms involving the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool in cancer research and therapeutic development, contributing to the understanding of nucleoside metabolism in malignancies. -
Nucleoside Metabolite
Aminoacetaldehyde is a nucleoside metabolite that plays a critical role in various biochemical pathways. It is involved in the metabolism of amino acids and nucleotides, facilitating cellular processes such as energy production and biosynthesis. This compound is valuable for research applications focusing on metabolic regulation and nucleotide synthesis. -
Purine Nucleoside Analog
DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog that serves as a key reagent in nucleic acid synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Its applications extend to cancer research, where it is utilized to explore therapeutic pathways and mechanisms in tumorigenesis. -
Purine Nucleoside Analog
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine is a purine nucleoside analog that exhibits potent antitumor activity. This compound is primarily utilized in the study of indolent lymphoid malignancies. Its biological mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic applications. -
Guanosine Analog
N2-[(N,N-Dimethyl amino]methylene-N1-methyl-2’-O-methylguanosine is a guanosine analog that targets Toll-like receptor 7 (TLR7) to exert its biological effects. It demonstrates immunostimulatory activity, eliciting type I interferon responses that confer antiviral properties in various animal models. This compound is valuable for researching the modulation of immune responses and the development of antiviral therapeutics. -
Adenosine Analog
N-Benzoyl-2′-O-2-propyn-1-yladenosine is an adenosine analog with the potential to act as a smooth muscle vasodilator and inhibit cancer progression. This compound features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc). It serves as a valuable tool in chemical research, particularly for applications involving bioconjugation and the development of novel therapeutics. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a purine nucleoside analog that exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on evaluating the effects of purine metabolism in oncology and therapeutics. -
Purine Nucleoside Analog
2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is employed in various studies aimed at understanding the therapeutic potential of nucleoside analogs in oncological applications. -
Purine Nucleoside Analog
4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog with significant antitumor activity. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its ability to interfere with cellular proliferation highlights its potential in cancer research and therapeutic applications. -
Purine Nucleoside Analog
Rev dC(Bz)-5'-amidite is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, and can induce apoptosis in cancer cells. This compound is valuable for research applications focusing on cancer therapeutics and the study of nucleoside metabolism. -
Purine Nucleoside Analog
N-Benzoyl-3′-O-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic development. This compound is utilized in studies aimed at understanding the effects of purine analogs on cellular processes and their potential in oncology. -
Thymidine Analog
5-Benzylaminocarbonyl-2’-O-methyluridine is a thymidine analog that primarily targets the incorporation of nucleotides into DNA. This compound exhibits insertional activity towards replicated DNA, making it a valuable tool for studying DNA synthesis and cell labeling. It is widely used in research applications involving nucleic acid metabolism and monitoring cellular processes. -
5-Hydroxyisourate Product
2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline functions primarily as a substrate in the hydrolysis of 5-hydroxyisourate. This compound is involved in biochemical pathways leading to the production of (S)-allantoin through stereoselective decarboxylation, mediated by 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. Its biological activity is essential for research applications in purine metabolism and nitrogenous waste elimination pathways in various organisms. -
Purine Nucleoside Analog
N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research. Its mechanisms of action are essential for studies focused on developing novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
5’-Azido-5’-deoxyuridine is a purine nucleoside analog that exhibits potent antitumor activity, primarily targeting indolent lymphoid malignancies through mechanisms such as DNA synthesis inhibition and apoptosis induction. This compound serves as a valuable click chemistry reagent, featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN functionalities, making it a versatile tool for bioconjugation applications in chemical biology and drug discovery. -
Purine Nucleoside Analog
2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mode of action involves the inhibition of DNA synthesis and the induction of apoptosis. This compound is utilized in various research applications aiming to explore therapeutic strategies in oncology and the mechanisms underlying cancer cell proliferation and survival. -
5’-AMP Analogue
6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP) that targets the 5’-AMP structure for chemical modification. This compound allows for selective modifications at position 6 using diverse nucleophiles, making it a valuable tool for researchers exploring nucleotide interactions and modifications. Its applications extend to studies in enzymatic processes and the development of modified nucleotides for therapeutic purposes. -
Purine Nucleoside Analog
2′-Chloro-2′-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in malignant cells, making it a valuable tool in cancer research and therapeutic applications. This compound is essential for studies aimed at understanding the effects of nucleotide analogs on cell proliferation and tumor development. -
Purine Nucleoside Analog
2-Amino-9-(2-β-C-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mode of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on exploring therapeutic strategies for hematological cancers and understanding the mechanisms of nucleoside analogue efficacy. -
Purine Nucleoside Analog
5-Ethyl-4-thiouridine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is ideal for studies focused on understanding the effects of nucleoside analogs in tumor biology and therapeutic development. -
Purine Nucleoside Analog
3’-Deoxy-5-methoxyuridine is a purine nucleoside analog that primarily acts by inhibiting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. It serves as a valuable tool for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
3'-Azido-3'-deoxyinosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. As a versatile click chemistry reagent, it features an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified compounds, making it useful for bioconjugation applications in chemical biology. -
Adenosine Analog
8-Benzyloxyadenosine is an adenosine analog that primarily targets adenosine receptors to elicit biological responses. This compound exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. It serves as a valuable tool for research in cardiovascular biology and cancer therapeutics. -
Purine Nucleoside Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-levulinyl-2’-deoxyadenosine is a purine nucleoside analog that plays a crucial role in molecular biology research. This compound exhibits significant antitumor activity against indolent lymphoid malignancies, primarily through mechanisms that inhibit DNA synthesis and induce apoptosis. It serves as a valuable tool for studying cancer biology and developing potential therapeutic strategies aimed at lymphoid cancers. -
Nucleoside Metabolite
1β-Methylseleno-N-acetyl-D-galactosamine (MeSebGalNac) is a nucleoside metabolite that serves as a seleno-containing analog of N-acetyl-D-galactosamine. It exhibits significant biological activity by participating in cellular methylation processes and potentially affecting selenoamino acid metabolism. This compound is utilized in studies focused on selenoprotein biology, nucleoside metabolism, and their implications in cancer and other diseases. -
Purine Nucleoside Analog
N6-Benzoyl-7'-OH-morpholino adenine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized in studies exploring therapeutic strategies and the underlying biological processes in cancer progression.
