Fig. 1 · Structure

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2′-Chloro-2′-deoxyuridine

Purine Nucleoside Analog

2′-Chloro-2′-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in malignant cells, making it a valuable tool in cancer research and therapeutic applications. This compound is essential for studies aimed at understanding the effects of nucleotide analogs on cell proliferation and tumor development.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 4753-04-2
Applications Purine Nucleoside Analog
Formula C9H11ClN2O5
Molecular Weight 262.65
SMILES
O[C@H]1[C@@H](Cl)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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