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3′-Bromo-3′-deoxythymidine

Purine Nucleoside Analog

3′-Bromo-3′-deoxythymidine is a purine nucleoside analog that exhibits significant antitumor activity primarily through the inhibition of DNA synthesis. This compound is effective against indolent lymphoid malignancies, contributing to apoptosis induction and disrupting cellular proliferation. It serves as a valuable tool in cancer research, particularly for exploring therapeutic strategies targeting nucleoside metabolism and DNA replication processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	99785-51-0
Applications	Purine Nucleoside Analog
Formula	C₁₁H₁₄BrNO₄
Molecular Weight	304.14
SMILES	OC[C@@H]1[C@@H](Br)C[C@H](C2C(NC(C(C)=C2)=O)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.