Fig. 1 · Structure
Documents & Downloads
Rev dC(Bz)-5'-amidite
Purine Nucleoside Analog
Rev dC(Bz)-5'-amidite is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, and can induce apoptosis in cancer cells. This compound is valuable for research applications focusing on cancer therapeutics and the study of nucleoside metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 140712-83-0 |
| Applications | Purine Nucleoside Analog |
| Formula | C46H52N5O8P |
| Molecular Weight | 833.91 |
| SMILES | O=C1N=C(NC(C2=CC=CC=C2)=O)C=CN1[C@@H]3O[C@@H]([C@H](C3)OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)COP(N(C(C)C)C(C)C)OCCC#N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.