6-Cl-5'-PuMP

Catalog No.: A56196
5’-AMP Analogue
6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP) that targets the 5’-AMP structure for chemical modification. This compound allows for selective modifications at position 6 using diverse nucleophiles, making it a valuable tool for researchers exploring nucleotide interactions and modifications. Its applications extend to studies in enzymatic processes and the development of modified nucleotides for therapeutic purposes.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP) that targets the 5’-AMP structure for chemical modification. This compound allows for selective modifications at position 6 using diverse nucleophiles, making it a valuable tool for researchers exploring nucleotide interactions and modifications. Its applications extend to studies in enzymatic processes and the development of modified nucleotides for therapeutic purposes.
Product Information
Catalog NumA56196
FormulaC10H12ClN4O7P
Molecular Weight366.65
CAS Number5843-59-4
SMILESO[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3Cl)O[C@@H]1COP(O)(O)=O
Synonyms6-Chloropurine 5'-ribonucleotide
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