Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is particularly useful in studies exploring the molecular pathways involved in tumor growth and resistance. -
Adenosine Analog
2'-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has potential applications in inhibiting cancer progression. Its mechanism of action makes it a valuable tool for researchers studying cardiovascular function and cancer therapeutics. -
Nucleoside Metabolite
(Z)-But-1-ene-1,2,4-tricarboxylate, also known as cis-Homoaconitate, is a nucleoside metabolite that plays a crucial role in metabolic pathways. It has been implicated in various biological processes and can be utilized in research applications focused on nucleoside metabolism and related biochemical pathways. Its biochemical activities make it a valuable tool for investigating metabolic disorders and enzyme activity in cellular studies. -
Purine Nucleoside Analog
8-Benzyloxy-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits potent antitumor activity. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it useful in the study of indolent lymphoid malignancies. This compound is valuable for research applications in cancer biology and therapeutic development targeting nucleoside metabolism. -
Purine Nucleoside Analog
2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog that targets a variety of biological pathways. This compound exhibits broad antitumor activity, making it particularly relevant in the study of indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis, underscoring its potential as a therapeutic agent in cancer research. -
Histidine Metabolite
D-Erythro-1-(imidazol-4-yl)glycerol 3-phosphate is an important metabolite in the histidine metabolism pathway. This compound has potential utility as a biomarker for epilepsy, providing insights into its biochemical underpinnings. It serves as a valuable tool for researchers studying metabolic processes related to histidine and their implications in neurological disorders. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-3-deazauridine is a purine nucleoside analog that exerts its biological activity by inhibiting DNA synthesis and inducing apoptosis. This compound demonstrates significant antitumor efficacy, particularly against indolent lymphoid malignancies. Research applications include investigating the mechanisms of action of nucleoside analogs in cancer therapy. -
Purine Nucleoside Analog
2-Deoxy-2’-deoxy-5’-(4,4’-dimethoxytrityl)uridine is a purine nucleoside analog primarily targeting DNA synthesis. This compound exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA replication and the induction of apoptosis in cancer cells, making it a valuable reagent for cancer research and therapeutic development. -
Nucleoside Metabolite
6β-Hydroxy-17β-estradiol is a nucleoside metabolite that serves as an important intermediate in estrogen metabolism. This compound exhibits key biological activities related to the modulation of estrogen receptor signaling pathways. It is valuable for research applications focused on understanding hormonal regulation, endocrine disorders, and estrogen-related diseases. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-6-azauridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is useful in cancer research focused on understanding nucleoside metabolism and developing new therapeutic approaches for lymphoid cancers. -
PNP Inhibitor
BCX-5 is a selective inhibitor of purine nucleoside phosphorylase (PNP), offering an inhibitory potency with a Ki value of 0.08 μM. This compound is known to impede cell proliferation and modulate mixed lymphocyte reactions by elevating levels of inosine and guanosine in plasma. BCX-5 is valuable for research applications in immunology, providing insights into purine metabolism and lymphocyte function. -
Purine Nucleoside Analog
2′,3′-Anhydroadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Nucleotide Sugar
UDP-6-azido-6-Deoxy-D-Glc is a nucleotide sugar that serves as a valuable tool for biochemical research. This compound can be utilized for the selective labeling of 5-hydroxymethylcytosine (5-hmC) in genomic DNA, facilitating studies related to epigenetics and gene regulation. Its unique azide functionality allows for click chemistry applications, enabling further exploration of nucleotide sugar biosynthesis and modification processes. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine is a purine nucleoside analog known for its antitumor activity, particularly in indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. -
Thymidine Analog
5-[3-[(Trifluoroacetyl)amino]propyl]uridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is valuable for labeling cells and monitoring DNA synthesis in various research applications. Its structural similarity to thymidine allows for effective incorporation into DNA, facilitating studies in cellular proliferation and genetic analysis. -
Purine Nucleoside Analog
N6-Benzoyl-2’-chloro-2’-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is commonly utilized in studies aimed at understanding the molecular pathways of cancer development and therapeutic response. -
Thymidine Analog
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analog exhibiting insertional activity towards replicated DNA. This compound is utilized for cellular labeling and tracking of DNA synthesis. It contains an azide group, making it a valuable click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, offering versatility in chemical biology applications. -
DNA Methylation Inhibitor
Dihydro-5-azacytidine is a DNA methylation inhibitor that is incorporated into the DNA structure, disrupting normal methylation processes. This compound exhibits antitumor activity, making it a valuable tool for cancer research. Its properties are relevant for studies focused on epigenetic regulation and the development of therapeutic strategies targeting DNA methylation. -
Purine Nucleoside Analog
2-Chloro-N6-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research applications in cancer biology and therapeutic development. This compound is suitable for studies investigating the molecular pathways involved in tumor progression and treatment response. -
Uridine Analog
4'-Cyanouridine is a uridine analog that serves as a valuable tool for exploring the biological functions of uridine in various physiological contexts. Its potential antiepileptic properties make it a candidate for studying anticonvulsant and anxiolytic activities. Additionally, 4'-Cyanouridine may contribute to the development of novel antihypertensive therapies, facilitating research into its therapeutic applications. -
Purine Nucleoside Analog
5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog that functions by inhibiting DNA synthesis and promoting apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action make it a valuable tool in cancer research, providing insights into therapeutic strategies for nucleoside-based treatments. -
Nucleoside Metabolite
2-Oxo-(4R)-hydroxy-5-aminovaleric acid is a nucleoside metabolite with critical implications in cellular metabolism. It plays a significant role in the regulation of amino acid pathways and may influence nucleic acid synthesis. This compound is utilized in research to study metabolic pathways and their effects on cellular functions. -
Purine Nucleoside Analog
5-(Trifluoromethyl)uridine is a purine nucleoside analogue that exhibits significant anti-tumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is widely utilized in cancer research to elucidate therapeutic strategies and evaluate potential treatment pathways. -
Purine Nucleoside Analog
1,N6-Etheno-ara-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is primarily utilized in studies focused on the development of novel therapeutic strategies for hematological cancers. -
Uridine Analog
N3-Allyluridine is a uridine analog that targets various biological pathways associated with nucleoside metabolism. It has demonstrated potential in exploring anticonvulsant and anxiolytic activities, positioning it as a useful tool for research in epilepsy and anxiety disorders. Additionally, N3-Allyluridine can aid in the development of novel antihypertensive agents, advancing the understanding of cardiovascular pharmacology. -
Purine Nucleoside Analog
1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog that exhibits significant antitumor activity. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for targeting indolent lymphoid malignancies. This compound is instrumental in cancer research and therapeutic studies focused on nucleoside analogs. -
Purine Nucleoside Analog
N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog that targets key pathways in cellular metabolism. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exerts its effects by targeting DNA synthesis pathways. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms including the inhibition of DNA replication and the induction of apoptosis. It is a valuable tool for researchers investigating cancer therapies and the pharmacological properties of nucleoside analogs. -
Purine Nucleoside Analog
9-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-6-chloro-9H-purine is a purine nucleoside analog with notable antitumor activity. This compound primarily targets indolent lymphoid malignancies, functioning through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. Its application in cancer research offers insights into therapeutic strategies against various malignancies, making it a valuable reagent for investigating purine metabolic pathways. -
Purine Nucleoside Analog
5'-Deoxy-5'-N-(2-chloroethyl)amino thymidine is a purine nucleoside analog that exerts its biological effects through inhibition of DNA synthesis and induction of apoptosis. This compound demonstrates broad antitumor activity, particularly against indolent lymphoid malignancies. Research applications include investigating the molecular mechanisms of cancer cell proliferation and exploring novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
3'-Amino-3'-deoxy-5-methyl uridine is a purine nucleoside analog that exhibits significant anticancer and antiviral properties. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it effective against indolent lymphoid malignancies. This compound is suitable for research applications focusing on cancer therapy and the study of nucleoside metabolism in cellular processes. -
Uridine Analog
2',5-Difluoro-2'-deoxy-1-arabinosyluracil is a uridine analog that primarily targets nucleoside metabolism. It exhibits potential antiepileptic effects, making it relevant for research into anticonvulsant and anxiolytic properties. Additionally, this compound may serve as a valuable tool in the development of novel antihypertensive agents, contributing to advancements in therapeutic strategies for various neurological and cardiovascular conditions. -
Adenosine Analog
5′-O-[(4-Cyanophenyl)methyl]-2′,3′-O-(1-methylethylidene)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory properties and demonstrates potential in inhibiting cancer cell proliferation. It is a valuable tool in research exploring the effects of adenosine signaling in cardiovascular diseases and cancer therapy. -
Purine Nucleoside Analog
2-Chloroinosine is a purine nucleoside analog that exerts significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of purine metabolism and the therapeutic potential of nucleoside analogs in various malignancies. -
Purine Nucleoside Analog
3'-beta-Azido-2',3'-dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. It functions primarily by inhibiting DNA synthesis and inducing apoptosis, thereby impeding cancer cell proliferation. This compound is useful in various research applications, including studies focused on cancer therapeutics and mechanisms of action of nucleoside analogs. -
Nucleoside Metabolite
12(R)-HPETE is a nucleoside metabolite that plays a significant role in the biosynthesis of lipids and signaling molecules. It is known to modulate various biological pathways, influencing processes such as inflammation and cell proliferation. This compound serves as a valuable tool for researchers investigating lipid metabolism and its implications in disease states. -
Nucleoside Metabolite
N-(2-Cyanoethyl)-L-glutamine is a nucleoside metabolite that acts as an important precursor in nucleotide biosynthesis. This compound can be utilized in metabolic studies to investigate the roles of nucleoside derivatives in cellular processes. Its relevance in research applications includes exploring pathways related to nucleotide metabolism and potential therapeutic implications in metabolic disorders. -
Purine Nucleoside Analog
5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent due to its azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules. -
Purine Nucleoside Analog
N6-Furfuryl-2-aminoadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on exploring anticancer therapies and understanding the underlying mechanisms of tumor growth and progression. -
Purine Nucleoside Analog
9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin is a purine nucleoside analog primarily known for its antitumor activity. This compound exerts its biological effects by inhibiting DNA synthesis and inducing apoptosis, making it relevant for the study of indolent lymphoid malignancies. Its unique structural modifications enhance its potential as a therapeutic agent in cancer research. -
Cytidine Analog
5-Iodo-2'-O-methylcytidine is a cytidine nucleoside analog that inhibits DNA methyltransferases. This compound exhibits significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. Its ability to modify epigenetic regulation provides insights into gene expression and cellular processes, supporting the exploration of novel therapeutic strategies. -
Adenosine Analog
N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an adenosine analog that acts primarily as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for various biological research applications. Its distinctive structural properties facilitate the study of adenosine receptor interactions and signaling pathways, contributing to the understanding of cardiovascular physiology and tumor biology. -
Purine Nucleoside Analog
2-Cyanoadenosine is a purine nucleoside analog that primarily targets cellular pathways involved in DNA synthesis and apoptosis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, making it a valuable compound for cancer research. Its ability to inhibit DNA synthesis contributes to its potential effectiveness in therapeutic applications for various malignancies. -
Purine Nucleoside Analog
2-[(3-Pyridyl) pyrrolidin-1-yl]-2’-deoxyinosine is a purine nucleoside analog that exerts its effects primarily by inhibiting DNA synthesis and inducing apoptosis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. It serves as a valuable tool for research applications focused on cancer biology and the development of novel therapeutic strategies. -
Cytidine Analog
2'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride is a cytidine nucleoside analog that specifically inhibits DNA methyltransferases. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. Its unique structure provides insights into nucleoside function and paves the way for therapeutic applications in epigenetic modulation. -
Nucleoside Metabolite
Bitocholate is a nucleoside metabolite involved in cellular metabolism. It plays a significant role in regulating nucleoside levels and may impact various biological pathways. Its applications in research include studies on nucleoside metabolism and the exploration of related therapeutic targets. -
Nucleoside Metabolite
11(S)-HPODE is a nucleoside metabolite that plays a critical role in cellular signaling and metabolic regulation. This compound is known to exhibit significant biological activity by modulating lipid peroxidation and promoting inflammatory responses. It is utilized in research applications focused on oxidative stress, inflammation, and related diseases, providing valuable insights into cellular processes and potential therapeutic interventions. -
Nucleoside Metabolite
2-(Dimethylamino)ethylphosphonic acid is a nucleoside metabolite that functions primarily as an intermediate in phosphate metabolism. This compound plays a crucial role in biochemical pathways associated with nucleotide synthesis and degradation. Its applications in research include studies on cellular signaling, metabolic regulation, and the effects of phosphonates in various biological systems. -
Purine Nucleoside Analog
5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a purine nucleoside analog that demonstrates significant antitumor activity against indolent lymphoid malignancies. Its anticancer effects primarily involve the inhibition of DNA synthesis and the induction of apoptotic pathways. This compound is valuable for research applications focused on cancer therapeutics and the mechanistic study of nucleoside analogs in oncology. -
Nucleoside Metabolite
Formylisoglutamine is a nucleoside metabolite that plays a crucial role in cellular metabolism. It is involved in the regulation of purine and pyrimidine biosynthesis, influencing various biological processes. This compound has potential applications in research related to metabolic pathways and the study of nucleoside derivatives in cellular function.
