5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analog exhibiting insertional activity towards replicated DNA. This compound is utilized for cellular labeling and tracking of DNA synthesis. It contains an azide group, making it a valuable click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, offering versatility in chemical biology applications.
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analog exhibiting insertional activity towards replicated DNA. This compound is utilized for cellular labeling and tracking of DNA synthesis. It contains an azide group, making it a valuable click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, offering versatility in chemical biology applications.
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