5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent due to its azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules.
5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent due to its azide functional group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain alkyne groups, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
