Nucleoside Antimetabolite/Analog

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  1. Uridine Analog

    5’(R)-C-Methyluridine is a uridine analog that serves as a valuable tool in biochemical research. This compound is primarily employed to investigate potential antiepileptic effects, as well as to assess anticonvulsant and anxiolytic activities. Additionally, it holds promise in the development of novel antihypertensive agents, expanding the understanding of uridine's therapeutic applications.
  2. Purine Nucleoside Analog

    5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog that exhibits significant antitumor activity. This compound primarily targets the inhibition of DNA synthesis and induces apoptosis, making it valuable in the study of indolent lymphoid malignancies. Its unique structural modifications enhance its effectiveness in various cancer research applications, particularly in understanding the biology of tumor cell proliferation and survival.
  3. Purine Nucleoside Analog

    N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This reagent can be utilized to elucidate the effects of nucleoside modifications on cellular processes and therapeutic responses.
  4. Purine Nucleoside Analog

    2'-Deoxy-N6-(4-methoxybenzyl)adenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This reagent serves as a crucial compound for studying cellular responses to nucleoside analogs and their potential in oncology.
  5. Nucleoside Metabolite

    N6-(5-Oxo-D-isoleucyl)-L-lysine is a nucleoside metabolite that serves as a key intermediate in nucleotide biosynthesis. This compound is utilized in research applications focused on metabolic pathways involving nucleotides and amino acids. Its biological activity offers insights into cellular metabolism and potential therapeutic targets for metabolic disorders.
  6. Thymidine Analog

    1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analog that targets DNA replication processes. This compound exhibits insertional activity within replicated DNA, making it a valuable tool for labeling cells and monitoring DNA synthesis. It is applicable in studies of nucleic acid dynamics and cellular proliferation.
  7. Purine Nucleoside Analog

    1,2-Di-O-acetyl-3,5-di-O-benzyl-D-xylofuranose is a purine nucleoside analog. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. The compound's anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies.
  8. Purine Nucleoside Analog

    1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)uridine is a purine nucleoside analog that exhibits significant antitumor activity, specifically targeting indolent lymphoid malignancies. Its primary mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic strategies against various malignancies.
  9. Purine Nucleoside Analog

    5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is a purine nucleoside analog known for its significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily exerts its effects by inhibiting DNA synthesis and inducing apoptosis in cancer cells. It serves as a valuable tool in cancer research, aiding in the exploration of therapeutic strategies and the development of novel anti-cancer agents.
  10. Purine Nucleoside Analog

    2′,3′-Dideoxy-3′-fluoroadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is useful in studies focused on the therapeutic potential of nucleoside analogs and their roles in cancer treatment strategies.
  11. Purine Nucleoside Analog

    2-Amino-6-chloropurine-9-beta-D-(2’-deoxy-3’,5’-di-O-(p-toluoyl))riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and promoting apoptosis, making it a valuable tool in cancer research. Its unique structural features also enable exploration of therapeutic strategies targeting purine metabolism in neoplastic cells.
  12. Cytidine Analog

    3’-beta-C-Methylcytidine is a cytidine nucleoside analog that primarily targets DNA methyltransferases. This compound demonstrates significant anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. It is suitable for studies focused on epigenetic regulation and therapeutic interventions aimed at altering DNA methylation patterns.
  13. Adenosine Analog

    3’-O-(2-Methoxyethyl)-2-aminoadenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory properties and has demonstrated potential in inhibiting cancer progression. Research applications include studying vascular biology, exploring therapeutic avenues in oncology, and investigating the signaling pathways mediated by adenosine receptors.
  14. Purine Nucleoside Analog

    2′-Deoxy-2-hydrazinyladenosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for investigating therapeutic approaches in oncology and understanding the molecular pathways involved in tumor cell proliferation and survival.
  15. Nucleoside Metabolite

    3α,7α-Dihydroxy-5β-cholestan-26-al is a nucleoside metabolite that plays a role in various biochemical pathways. This compound is involved in the metabolism of nucleosides and may exhibit significant biological activity in cellular processes. It is suitable for research applications focused on metabolic studies and the investigation of nucleoside-related mechanisms.
  16. Purine Nucleoside Analog

    TLR7 agonist 10 is a purine nucleoside analog that functions as a TLR7 activator. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. TLR7 agonist 10 is essential for research focused on cancer biology and therapeutic development.
  17. Purine Nucleoside Analog

    3’-Deoxy-O6-methyl inosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on understanding cancer biology and developing novel therapeutic strategies.
  18. Purine Nucleoside Analog

    3’-Deoxy-3’-fluoro-2-thiouridine is a purine nucleoside analog known for its significant antitumor activity. It targets indolent lymphoid malignancies and exerts its effects primarily through the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research, enabling studies on therapeutic strategies against various malignancies.
  19. Purine Nucleoside Analog

    6-Chloro-2-iodopurine-9-riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on understanding cancer biology and developing targeted therapies.
  20. Uridine Analog

    3'-Azido-3'-deoxy-4-deoxyuridine is a uridine analog featuring an azide functional group. This compound is utilized in click chemistry applications, specifically in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules. It may be instrumental in the study of anticonvulsant and anxiolytic activities, as well as in the development of new antihypertensive agents.
  21. Purine Nucleoside Analog

    2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analog that exhibits significant anticancer activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and the development of novel anticancer therapeutics.
  22. Nucleoside Metabolite

    α-Phocaecholic acid is a nucleoside metabolite that serves as a critical component in various biochemical pathways. This compound is known for its role in cellular signaling and metabolism, making it a valuable tool in research related to nucleoside functions. Its applications extend to studies in metabolic disorders and cellular processes, aiding researchers in understanding the underlying mechanisms of nucleoside metabolism.
  23. Purine Nucleoside Analog

    3′-Azido-2′,3′-dideoxy-5-hydroxyuridine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis, thereby disrupting cellular replication. It demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies, and promotes apoptosis in cancerous cells. This compound is useful in research focused on cancer treatment and the mechanisms of chemotherapeutic agents.
  24. Purine Nucleoside Analog

    5-(Aminomethyl)-2′,3′-O-(1-methylethylidene)-2-thiouridine is a purine nucleoside analog known for its significant antitumor activity. This compound targets indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It serves as a valuable reagent for cancer research aimed at understanding and developing therapies for lymphoid cancers.
  25. Hypoxanthine Analog

    2-Chloro-2'-deoxy-6-O-methylinosine is a hypoxanthine analog that serves as a potent modulator of various biological pathways. This compound exhibits significant anti-inflammatory properties and functions as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor, providing cytoprotection by inhibiting PARP activity and mitigating peroxynitrite-induced mitochondrial depolarization and superoxide production. Additionally, this analog can be utilized as an indicator of hypoxia in research settings, making it valuable for studies related to cellular response under low oxygen conditions.
  26. Adenosine Analog

    3',5'-TIPS-N-Ac-Adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has potential applications in inhibiting cancer progression. It is valuable for research related to vascular biology and oncology, facilitating the study of adenosine receptor signaling pathways and their therapeutic implications.
  27. Purine Nucleoside Analog

    5-(Trifluoromethyl)cytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which can lead to apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and the development of novel therapeutic strategies.
  28. Purine Nucleoside Analog

    2-Methoxy-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis in malignant cells. It is utilized in research focused on understanding and developing treatments for various lymphoid cancers.
  29. Purine Nucleoside Analog

    8-Bromo-3'-deoxyguanosine is a purine nucleoside analog known for its capacity to inhibit DNA synthesis. Its primary mechanism involves inducing apoptosis, contributing to its antitumor activity, particularly against indolent lymphoid malignancies. This compound is valuable in cancer research for studying cellular responses and therapeutic strategies in oncology.
  30. Purine Nucleoside Analog

    2′-Deoxy-2′-fluoro-4-deoxy-arabinouridine functions as a purine nucleoside analog. It exhibits significant antitumor activity, particularly effective against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for researchers studying cancer therapeutics and cellular response pathways.
  31. Purine Nucleoside Analog

    3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of purine metabolism and the therapeutic potential of nucleoside analogs in oncology.
  32. Purine Nucleoside Analog

    2-Chloro-2'-deoxy inosine is a purine nucleoside analog known for its antitumor properties. It effectively targets indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis in cancer cells. This compound is primarily utilized in research applications focused on cancer biology and the development of therapeutic strategies against lymphoid cancers.
  33. Nucleoside Metabolite

    L-2-Aminoadipate adenylate is a nucleoside metabolite that plays a critical role in amino acid biosynthesis and metabolism. This compound is involved in cellular energy processes and can serve as a substrate in ATP-dependent reactions. Its applications extend to studies in metabolic pathways and the regulation of amino acid availability, making it valuable for research in biochemistry and molecular biology.
  34. Purine Nucleoside Analog

    5’-O-Benzoyl-2’-O,4’-C-methyleneuridine is a purine nucleoside analog that exhibits significant antitumor activity by targeting indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer therapeutics and the biochemical pathways associated with cell proliferation and survival.
  35. Purine Nucleoside Analog

    3’-O-Acetyl-2’-deoxyuridine is a purine nucleoside analog that interferes with DNA synthesis, offering potential therapeutic avenues in cancer research. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis, making it a valuable tool for investigating cancer biology and developing new therapeutic strategies.
  36. Purine Nucleoside Analog

    5-O-Benzoyl-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the promotion of apoptosis. This compound is valuable for researchers investigating targeted therapies in cancer treatment.
  37. Nucleoside Metabolite

    1-Carboxyvinyl carboxyphosphonate is a nucleoside metabolite that acts as a potent inhibitor of various nucleoside-related enzymes. It exhibits significant biological activity in modulating nucleotide metabolism, making it a valuable tool for studying metabolic pathways in cellular function and disease states. This reagent is useful for research applications in nucleoside metabolism and enzyme inhibition assays.
  38. Adenosine Analog

    8-(Methylamino)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant vasodilatory effects on smooth muscle and has been demonstrated to possess anti-cancer properties by inhibiting tumor progression. It is utilized in various research applications related to vascular biology and oncology.
  39. Purine Nucleoside Analog

    2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies focused on therapeutic interventions in hematological cancers and the exploration of nucleoside analogs in chemotherapy.
  40. Nucleoside Compound

    β-D-Ribofuranose analogue 1 is a nucleoside compound that serves as a structural analog of ribofuranose. It is primarily utilized in RNA synthesis, enabling researchers to study RNA-related processes and functions. This compound is essential for applications in nucleic acid research and the development of RNA-based therapeutics.
  41. Cytidine Analog

    3’-O-(2-Methoxyethyl)-5-methylcytidine is a nucleoside analog targeting DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and epigenetic studies. It is particularly useful for investigating the role of DNA methylation in gene regulation and cellular processes.
  42. Purine Nucleoside Analog

    1-(alpha-L-Threofuranosyl)cytosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research and therapeutic applications. This compound is a key tool for studies focused on the mechanisms of nucleoside analogs in cancer treatment strategies.
  43. Purine Nucleoside Analog

    N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)]propylpseudouridine is a purine nucleoside analog primarily targeting DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms that include the inhibition of DNA replication and the induction of apoptosis. Its applications in cancer research make it a valuable tool for studying nucleoside analog effects in therapeutic interventions.
  44. Purine Nucleoside Analog

    5'-Protected 2,2'-anhydrouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action primarily involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is an essential tool for research focused on cancer biology and therapeutic development, providing insights into nucleoside metabolism and therapeutic strategies.
  45. Adenosine Analog

    3'-β-C-Ethynyl-N6,N6-dimethyladenosine is an adenosine analog with significant implications in vascular research and oncology. This compound serves as a smooth muscle vasodilator and has demonstrated potential in inhibiting cancer progression. Additionally, it functions as a click chemistry reagent due to its alkyne group, allowing for copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules, making it a valuable tool for bioconjugation and labeling applications in chemical biology.
  46. Thymidine Analog

    2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is a thymidine analog that demonstrates insertional activity within replicated DNA. This compound is valuable for labeling cells and monitoring DNA synthesis, making it an essential tool in molecular biology and genetic research. Its structure enables precise tracking of cellular processes related to DNA replication and repair.
  47. Purine Nucleoside Analog

    2’-β-C-Methyl-6-azauridine is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis, making it a valuable reagent for cancer research and therapeutic studies focused on lymphoid tumors.
  48. Purine Nucleoside Analog

    2’-O-Acetyl-3’-azido-5’-O-(4-methylbenzoyl)-3’-deoxyuridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, facilitating its efficacy in cancer research. Additionally, this compound serves as a versatile click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, DBCO, or BCN groups. This makes it a valuable tool for bioconjugation and molecular labeling studies.
  49. Coenzyme A Derivative

    (25R)-3Alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA is a coenzyme A derivative that serves as an important substrate in lipid metabolism. Its primary mechanism involves the formation of acyl-CoA thioesters, which play a critical role in fatty acid synthesis and degradation. This compound can be utilized in research focused on lipid biochemistry, metabolic pathway studies, and the regulation of cholesterol homeostasis.
  50. Purine Nucleoside Analog

    3’-Deoxy-3’-fluoro-5-methyl-xylo-uridine is a purine nucleoside analog primarily involved in inhibiting DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. This compound is valuable for research applications focused on cancer biology and therapeutic development.

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