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2-Chloro-2'-deoxy-6-O-methylinosine

Hypoxanthine Analog

2-Chloro-2'-deoxy-6-O-methylinosine is a hypoxanthine analog that serves as a potent modulator of various biological pathways. This compound exhibits significant anti-inflammatory properties and functions as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor, providing cytoprotection by inhibiting PARP activity and mitigating peroxynitrite-induced mitochondrial depolarization and superoxide production. Additionally, this analog can be utilized as an indicator of hypoxia in research settings, making it valuable for studies related to cellular response under low oxygen conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	146196-07-8
Applications	Hypoxanthine Analog
Formula	C₁₁H₁₃ClN₄O₄
Molecular Weight	300.70
SMILES	O[C@@H]1[C@@H](CO)O[C@H](C1)N(C=N2)C3=C2C(OC)=NC(Cl)=N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.