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2'-Deoxy-8-methylthioguanosine

Purine Nucleoside Analog

2'-Deoxy-8-methylthioguanosine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies focused on therapeutic interventions in hematological cancers and the exploration of nucleoside analogs in chemotherapy.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	157946-92-4
Applications	Purine Nucleoside Analog
Formula	C₁₁H₁₅N₅O₄S
Molecular Weight	313.33
SMILES	O[C@@H]1[C@@H](CO)O[C@@H](N2C(N=C(N)NC3=O)=C3N=C2SC)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.