Catalog No.
Product Name
Application
Product Information
Citations
-
Purine Nucleoside Analog
2’-Deoxy-N4-ethyl-5-methylcytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, thereby disrupting the proliferation of cancer cells. It serves as a valuable tool in cancer research, aiding in the study of nucleoside analog mechanisms and potential therapeutic applications. -
Purine Nucleoside Analog
3’-Deoxy-methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications in cancer biology, enabling the exploration of therapeutic strategies targeting DNA replication and cellular survival pathways. -
Adenosine Analog
2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-Methyl-beta-D-ribofuranosyl)]-9H-purine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits biological activities such as promoting smooth muscle vasodilation and potentially inhibiting cancer progression. It is a valuable reagent for researchers investigating vascular biology, cancer therapeutics, and adenosine signaling pathways. -
Purine Nucleoside Analog
7-Ethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptotic pathways. This compound serves as a valuable tool in cancer research, facilitating studies on therapeutic strategies targeting nucleoside metabolism and cancer cell proliferation. -
Purine Nucleoside Analog
N6-iso-Propyladenosine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of nucleoside analogs on cellular proliferation and apoptosis in various cancer models. -
Adenosine Analog
2-Amino-N-(3-methyl-2-buten-1-yl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has been implicated in the inhibition of cancer progression. It serves as a valuable tool for research in vascular biology and cancer therapeutics, facilitating the exploration of adenosine receptor signaling pathways and their implications in various disease states. -
Uridine Analog
2′-Deoxy-2′-fluoro-5-methoxy-arabinouridine is a uridine analog that targets nucleotide metabolism. This compound exhibits potential antiepileptic properties and serves as a valuable tool for investigating anticonvulsant and anxiolytic activities. Additionally, it can be utilized in the development of novel antihypertensive agents, contributing to research in neurological and cardiovascular therapeutics. -
Nucleoside Metabolite
4α-Methyl-5α-ergosta-8,14,24(28)-trien-3β-ol is a nucleoside metabolite known for its role in cellular metabolism. This compound exhibits significant biological activity and is used in research applications focusing on metabolic pathways and nucleoside derivatives. Its unique structural properties make it a valuable tool for studying biochemical processes related to nucleoside function. -
Purine Nucleoside Analog
1,4-Anhydro-2,3-O-isopropylidene-5-O-t-butyldiphenylsilyl-4-thio-D-ribitol is a purine nucleoside analog that exhibits potent antitumor activity. This compound acts primarily by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its ability to mimic natural nucleosides allows for exploration in cancer research and therapeutic development. -
Cinnamic acid Derivative
Trans-2,3-Dihydroxycinnamate is a derivative of cinnamic acid that functions as a potent antioxidant. This compound exhibits significant biological activity that may contribute to its role in various biochemical pathways. It is useful in research applications focused on the investigation of antioxidant mechanisms and the metabolic effects of cannabinoids. -
Purine Nucleoside Analog
DMTr-TNA-C(Bz)-amidite is a purine nucleoside analog that serves as a critical component in nucleic acid synthesis. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research applications focused on therapeutic development and molecular studies. -
Purine Nucleoside Analog
N6-Methyl-2-methyl thioadenosine is a purine nucleoside analog that serves as a promising reagent in cancer research. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. Its mechanisms of action make it valuable for studying therapeutic strategies in oncology. -
Purine Nucleoside Analog
7,8-Dihydro-8-oxo-7-propargyl-3’-deoxy-3’-fluoro-xylo-guanosine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, expanding its utility in chemical biology and drug development research. -
Purine Nucleoside Analog
5'-Azido-2',5'-dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is utilized for studying the effects of nucleoside analogs in cellular and molecular contexts related to oncogenesis and therapeutic resistance. -
Purine Nucleoside Analog
9-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound impedes DNA synthesis and promotes apoptosis, contributing to its efficacy in cancer therapeutics. It is a valuable tool in research focused on understanding cancer biology and developing novel treatment strategies. -
Oligonucleotide
m7GpppCmpG is an oligonucleotide that serves as an M7GpppNpG trinucleotide cap analogue. This compound is essential for the synthesis of RNA molecules featuring cap 0 or cap 1 structures, facilitating studies in RNA biology and gene expression. It provides researchers with a valuable tool for exploring mRNA modifications and their implications in various biological processes. -
Guanosine Analog
N2-iBu-5’-O-DMTr-2’-O-propargylguanosine-3’-CED-phosphoramidite is a guanosine analog that serves as a critical tool for studying RNA synthesis and cellular responses. This compound exhibits immunostimulatory properties, with the potential to induce type I interferons in various animal models, contributing to antiviral effects. Its mechanism of action is linked to the activation of Toll-like receptor 7 (TLR7), making it valuable for research in immunology and antiviral therapeutics. -
Purine Nucleoside Analog
2-Amino-N,N-dimethyl-2′-C-methyladenosine is a purine nucleoside analog with significant biological activity against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized in studies aiming to elucidate the therapeutic potentials of nucleoside analogs in oncology. -
Glycoside
Nyasicoside is a norlignan glycoside with a primary mechanism targeting cardiac function. It exhibits significant antiarrhythmic activity, particularly in mitigating ouabain-induced arrhythmias in guinea pig heart preparations. This compound is valuable for research focused on cardiac physiology and the development of treatments for arrhythmias. -
Purine Nucleoside Analog
8-Chloro-2'-O-methyl adenosine is a purine nucleoside analog that exhibits potent antitumor activity. It primarily targets indolent lymphoid malignancies, utilizing mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research into cancer biology and therapeutic applications targeting malignancies. -
Adenosine Analog
5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine is an adenosine analog that serves as a key modulator of adenosine receptors. This compound exhibits vasodilatory effects on smooth muscle and has potential applications in cancer research due to its ability to inhibit tumor progression. It is particularly useful for studies investigating the roles of adenosine in vascular biology and oncology. -
Purine Nucleoside Analog
N4-Benzoyl-7'-OH-N-trityl morpholino cytosine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. This compound serves as a valuable tool in cancer research, facilitating the study of mechanisms underlying nucleotide metabolism and potential therapeutic interventions. -
Purine Nucleoside Analog
3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms that include the inhibition of DNA synthesis and the induction of apoptosis. Its applications in chemical research may support the development of novel therapeutic strategies in oncology. -
Cytidine Analog
N4-Benzoyl-5’-O-DMT-3’-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog that functions as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor properties, making it valuable in cancer research. Its unique chemical structure enables investigations into epigenetic modifications and therapeutic approaches targeting DNA methylation pathways. -
Adenylate Cyclase Inhibitor
MANT-GppNHp is a competitive inhibitor of adenylate cyclase (AC) that serves as a fluorescently labeled GTP analogue. It specifically interacts with the hydrophobic pocket adjacent to the AC catalytic site through its MANT group, effectively obstructing the binding of ATP. This compound is valuable for investigating diseases characterized by elevated AC activity, such as cholera, and offers insights into cellular signaling pathways. -
Dideoxynucleotide
ddCTPαS is a dideoxynucleotide that acts as a chain-terminating nucleotide in DNA synthesis. Its primary application lies in DNA sequencing, where it facilitates the determination of nucleic acid sequences by preventing further elongation of the DNA strand during polymerization. Researchers utilize ddCTPαS to enhance the accuracy and efficiency of genetic analysis and sequencing methodologies. -
Cytidine Analog
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine is a cytidine nucleoside analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research. It is useful for studying epigenetic regulation and therapeutic strategies targeting methylation-driven processes in various malignancies. -
Guanosine Analog
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-methylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has the potential to induce type I interferons in various animal models, resulting in antiviral effects. Its mechanism of action makes it a valuable reagent for research applications related to immune response and antiviral drug development. -
Purine Nucleoside Analog
2-Chloro-6-(thiophen-3-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable reagent for research in cancer therapeutics. Its unique structure allows for exploration in pharmacological studies and therapeutic applications targeting nucleoside metabolism. -
Dideoxynucleotide
ddGTPαS is a dideoxynucleotide analog that serves as a chain terminator in PCR assays. By incorporating ddGTPαS into the growing DNA strand, it inhibits further extension, allowing for precise control of amplification. This reagent is essential for applications in sequencing and studying DNA polymerization dynamics. -
Purine Nucleoside Analog
6-Methyl-9-(2-β-C-methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that exerts its effects by inhibiting DNA synthesis. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the induction of apoptosis and disruption of cellular proliferation, making it a valuable tool for cancer research. -
Adenosine Analog
2-Amino-N6,N6-dimethyl-2’-O-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits smooth muscle vasodilatory effects and has potential applications in inhibiting cancer progression. It is valuable for research in cardiovascular studies and oncology, providing insights into the therapeutic potential of adenosine-related pathways. -
Purine Nucleoside Analog
6-Methylpseudouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for studies focused on cellular proliferation and apoptosis pathways in neoplastic cells. -
Adenosine Analog
3’-beta-C-Methyl-N6-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory effects and has demonstrated potential in inhibiting cancer progression. Its unique structure allows for various research applications, particularly in studies focusing on cardiovascular function and tumor biology. -
Purine Nucleoside Analog
8-Amino-2′-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound in cancer research. This reagent is suitable for exploring therapeutic strategies in nucleotide metabolism and evaluating potential treatments for lymphoid cancers. -
Cytidine Analog
5-Vinylcytidine is a cytidine analog that functions primarily as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it valuable in cancer research and therapeutic investigations. Its ability to alter epigenetic modifications positions it as a useful tool for studying gene regulation and methylation patterns in various biological contexts. -
Purine Nucleoside Analog
2'-Amino-2'-deoxy-5-fluoro-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and the induction of apoptosis. This reagent is valuable for research in cancer biology and the development of novel therapeutic agents targeting nucleoside metabolism. -
Enzyme Substrate
Adenosine 5'-phosphosulfate serves as a substrate for bifunctional 3'-phospho-adenosine-5'-phosphosulfate synthases and related enzymes. This compound plays a critical role in sulfate activation and the synthesis of phosphoadenosine phosphosulfate, which is essential for sulfonate group transfers in biological systems. Its application in research includes studies on cellular sulfate metabolism and enzyme kinetics, providing insights into the regulation of various biochemical pathways. -
Purine Nucleoside Analog
5-Methyl-4'-thiocytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool in cancer research by helping to elucidate the molecular pathways involved in tumor growth and resistance. -
Purine Nucleoside Analog
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-4-deoxy-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focusing on nucleoside metabolism and the development of novel therapeutic strategies in oncology. -
Purine Nucleoside Analog
2-Amino-6-allyl thio-9-(beta-D-ribofuranosyl)-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound serves as a valuable tool for research applications focusing on cancer treatment strategies and the exploration of nucleoside analogs in therapeutic development. -
Purine Nucleoside Analog
2-Amino-2’,3’-bis-O-(2-methoxyethyl) adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer treatment and the exploration of nucleoside analogs in therapeutic development. -
Purine Nucleoside Analog
2'-Amino-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog with significant antitumor properties, specifically against indolent lymphoid malignancies. Its biological activity involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound in cancer research. This reagent can be utilized to explore mechanisms of action in cancer therapy and to evaluate its potential in drug development. -
Purine Nucleoside Analog
N2-Ethylguanosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. This compound exerts its anticancer effects through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. It serves as a valuable tool for research applications focused on cancer therapeutics and the study of nucleoside biochemistry. -
Purine Nucleoside Analog
2′-β-C-Methyl isoguanosine is a purine nucleoside analog that primarily targets nucleic acid synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its application in cancer research facilitates the exploration of therapeutic strategies for treating resistant forms of hematological malignancies. -
Purine Nucleoside Analog
2-Methyl-2’-deoxyadenosine is a purine nucleoside analog that exerts cytotoxic effects by inhibiting DNA synthesis. This compound is primarily investigated for its antitumor activity against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and disruption of cellular proliferation, making it relevant for cancer research applications. -
Purine Nucleoside Analog
2-Methylthio isopentenyladenosine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its unique mechanism makes it a valuable tool for research into cancer therapies and mechanisms of cellular proliferation. -
Guanosine Analog
N2-iso-Butyroyl-2’-O-propargylguanosine is a guanosine analog that primarily targets Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory activity and has been shown to induce type I interferons in various animal models, contributing to antiviral effects. Additionally, it serves as a click chemistry reagent due to its alkyne functional group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating advanced biochemical research applications. -
Nucleoside Metabolite
3-Phospho-D-glycerate is an important nucleoside metabolite that serves as an intermediate in glycolysis and gluconeogenesis. It is converted to 2-phospho-D-glycerate (2-PGA) through the action of the enzyme phosphoglycerate mutase. This compound is significant for research in metabolism, cellular energy production, and enzyme kinetics. Its role in metabolic pathways makes it a valuable reagent for studies in biochemistry and molecular biology. -
Purine Nucleoside Analog
3′-Deoxy-3′-iodothymidine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by interfering with nucleotide metabolism and inducing apoptotic pathways in cancer cells. This compound serves as an essential tool for research applications focused on cancer biology and therapeutic development.
