Fig. 1 · Structure

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2′-β-C-Methyl isoguanosine

Purine Nucleoside Analog

2′-β-C-Methyl isoguanosine is a purine nucleoside analog that primarily targets nucleic acid synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis in cancer cells. Its application in cancer research facilitates the exploration of therapeutic strategies for treating resistant forms of hematological malignancies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 714249-83-9
Applications Purine Nucleoside Analog
Formula C11H15N5O5
Molecular Weight 297.27
SMILES
OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C=NC3=C2NC(N=C3N)=O)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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