N6-iso-Propyladenosine

Catalog No.: A55662
Purine Nucleoside Analog
N6-iso-Propyladenosine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of nucleoside analogs on cellular proliferation and apoptosis in various cancer models.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN6-iso-Propyladenosine is a purine nucleoside analog with significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool in cancer research. This compound is useful for studying the effects of nucleoside analogs on cellular proliferation and apoptosis in various cancer models.
Product Information
Catalog NumA55662
FormulaC13H19N5O4
Molecular Weight309.32
CAS Number17270-23-4
SMILESO[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(NC(C)C)=NC=N3)O[C@@H]1CO
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