Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
2-Chloro-2’-β-C-methyl-6-N,N-dimethyladenosine is a purine nucleoside analog that primarily targets DNA synthesis pathways. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. Its use in research includes exploring mechanisms of cancer therapy and elucidating pathways involved in nucleoside metabolism. -
Guanosine Analog
3′-C-Methylguanosine is a guanosine analog that acts primarily as an immunostimulatory agent. This compound has been shown to induce the production of type I interferons in animal models, demonstrating notable antiviral effects. Its functional activity largely relies on the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for research into immune response and antiviral therapies. -
Purine Nucleoside Analog
3’-Deoxy-2’,5’-di-O-acetyl-8-hydroxyguanosine is a purine nucleoside analog that interferes with nucleotide metabolism and DNA synthesis. This compound demonstrates significant antitumor activity and is particularly effective against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development. -
Purine Nucleoside Analog
2'-O-Phthalimidopropyl cytidine is a purine nucleoside analog that primarily targets DNA synthesis pathways. Its notable biological activity includes inducing apoptosis in cancer cells, making it valuable for research focused on antitumor mechanisms. This compound is particularly relevant for studies involving indolent lymphoid malignancies and contributes to understanding cancer cell proliferation and survival. -
Nucleoside Metabolite
2-Methoxyestradiol-17beta 3-sulfate is a nucleoside metabolite that modulates various biological pathways through its interactions with estrogen receptors. This compound exhibits significant anti-proliferative and anti-angiogenic properties, making it a valuable tool in cancer research. Its role in cell signaling and metabolism supports its use in studies related to endocrine function and tumor biology. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound functions as a click chemistry reagent, featuring an azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) functionalized compounds, making it a valuable tool for chemical biology applications. -
Purine Nucleoside Analog
3’-O-Acetyl-N2-iso-Butyroyl-2’-deoxy-guanosine is a purine nucleoside analog that serves as a potent inhibitor of DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and disrupting cellular proliferation. Its versatile applications in cancer research make it a valuable tool for studying mechanisms of tumor growth and treatment strategies. -
Purine Nucleoside Analog
5'-Homocytidine is a purine nucleoside analog that exerts its effects primarily through the inhibition of DNA synthesis. This compound displays significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the induction of apoptosis and interference with cellular replication processes, making it a valuable tool for cancer research and therapeutic studies. -
Hydrocinnamic acid Metabolite
cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol is a metabolite involved in the dioxygenolytic catabolism of hydrocinnamic acid (3-phenylpropionic acid). This compound plays a crucial role in the degradation pathway of hydrocinnamic acid and is valuable for research into metabolic processes and enzymatic activity related to phenolic compounds. Its characterization can aid in understanding metabolic pathways and the environmental fate of hydrocinnamic acid derivatives. -
Purine Nucleoside Analog
8-Chloroguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and treatment strategies targeting nucleoside metabolic pathways. -
Purine Nucleoside Analog
1,2-Di-O-acetyl-3-deoxy-3-fluoro-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, making it a valuable tool in cancer research. Its ability to interfere with nucleic acid metabolism facilitates exploration into therapeutic strategies for hematological cancers. -
Glutathione-spermidine Conjugate
Bis(glutathionyl)spermine is a glutathione-spermidine conjugate that primarily targets oxidative stress and cellular redox balance. This compound demonstrates significant biological activity in modulating intracellular levels of reactive oxygen species (ROS) and enhancing cellular antioxidant capacity. It is utilized in research applications focused on cellular signaling, apoptosis, and the protective mechanisms of glutathione in various biological contexts. -
Nucleoside Metabolite
(3S)-2,3-Oxidosqualene acts as a nucleoside metabolite with significant biological relevance. This compound is involved in various biosynthetic pathways, particularly in sterol synthesis and cellular signaling. Research applications include investigations into cholesterol metabolism and the exploration of potential therapeutic targets in lipid-related diseases. -
Nucleoside Metabolite
2'-Deoxyinosine 5'-diphosphate (dIDP) is a nucleoside metabolite that serves as an intermediate in the synthesis of deoxyribonucleotides. It plays a crucial role in nucleic acid metabolism and is involved in various biochemical pathways related to DNA replication and repair. dIDP is valuable for research applications concerning nucleotide metabolism, enzymatic assays, and studies of cellular processes involving deoxynucleotides. -
Cytidine Analog
5-Bromo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine is a cytidine nucleoside analog that functions primarily by inhibiting DNA methyltransferases. This compound exhibits notable anti-metabolic and anti-tumor properties, making it a valuable tool in cancer research. Its unique structure and mechanism provide insights into nucleoside metabolism and potential therapeutic strategies for malignancies. -
Guanosine Analog
N2-iso-Butyroyl-3’-O-(methoxyethyl)guanosine is a guanosine analog that exhibits immunostimulatory properties. This compound has been shown to induce type I interferons in animal models, leading to antiviral effects. Its functional activity is linked to the activation of Toll-like receptor 7 (TLR7), making it a valuable tool for investigating immune responses and antiviral mechanisms in research. -
Purine Nucleoside Analog
7-Cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl) guanine acts as a purine nucleoside analog with significant antitumor activity, primarily targeting indolent lymphoid malignancies. Its anticancer effects are attributed to the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on understanding the mechanisms of action in cancer therapeutics. -
Purine Nucleoside Analog
2′-Amino-2′-deoxycytidine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is primarily utilized in research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine is a purine nucleoside analog that inhibits DNA synthesis. This compound exhibits significant antitumor activity against indolent lymphoid malignancies, with mechanisms that include the induction of apoptosis. It serves as a valuable tool in cancer research for understanding the effects of nucleoside modifications on tumor progression and treatment response. -
Adenosine Analog
N6-(3-Methoxybenzyl)-2’-C-methyl adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant biological activity as a smooth muscle vasodilator and demonstrates potential anti-cancer properties. It is suitable for research applications focused on vascular biology and cancer therapeutics. -
Purine Nucleoside Analog
1-(alpha-L-Threofuranosyl)thymine is a purine nucleoside analog that demonstrates significant antitumor activity, especially in the treatment of indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells, making it a valuable tool for studying cancer biology and therapeutic strategies. This compound is useful in the development of treatments targeting specific malignancies and contributes to advancing understanding in the field of oncology research. -
Adenosine Analog
N-(3-Methylbutyl)adenosine is an adenosine analog that functions primarily as a smooth muscle vasodilator. This compound has been shown to possess inhibitory effects on cancer progression, making it valuable for research in both cardiovascular and oncology studies. Its application in various biological assays highlights its potential as a therapeutic agent in the treatment of vascular and cancer-related diseases. -
Purine Nucleoside Analog
5’-Azido-5’-deoxy-2'-O-methyluridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and induction of apoptosis. Additionally, this compound functions as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This unique combination of biological activity and reactivity makes it valuable for various research applications in chemical biology. -
Adenosine Analog
N6-Methyl-2’-β-C-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound has demonstrated vasodilatory effects on smooth muscle and exhibits potential in inhibiting cancer progression. Its unique structure allows for various research applications related to adenosine signaling pathways and therapeutic interventions. -
Purine Nucleoside Analog
1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog that exhibits significant anti-tumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable compound for cancer research. This reagent is suited for studies aimed at understanding the molecular pathways involved in tumorigenesis and potential therapeutic interventions. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazinyl)pyridin-3-yl]purine acts as a purine nucleoside analog with significant implications for cancer research. This compound exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis. It is a valuable tool for studying cancer mechanisms and developing therapeutic strategies in oncology. -
Adenosine Analog
5’-O-(4,4’-Dimethoxytrityl)-N6-phenoxyacetyl adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory effects and has been implicated in the inhibition of cancer progression. It is a valuable reagent for research focused on vascular biology, immunology, and oncology, facilitating investigations into the therapeutic potential of nucleotide derivatives. -
Purine Nucleoside Analog
2′,3′-Didehydro-2′,3′-dideoxy-5-fluorouridine is a purine nucleoside analog that exhibits potent antitumor activity, particularly against indolent lymphoid malignancies. This compound primarily functions through the inhibition of DNA synthesis and the induction of apoptosis. It serves as an important tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
3'-Deoxy-3'-fluoro-6-azauridine is a purine nucleoside analogue that selectively inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by promoting cellular apoptosis and disrupting nucleotide metabolism. It is a valuable tool for research applications focused on cancer biology and therapeutic investigations targeting nucleoside metabolism. -
Hypoxanthine Analog
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog that selectively targets key metabolic pathways involving purine metabolism. This compound exhibits notable anti-inflammatory properties and serves as a potential endogenous inhibitor of poly(ADP-ribose) polymerase (PARP). Its cytoprotective effects are attributed to the inhibition of PARP activity, which prevents peroxynitrite-induced mitochondrial depolarization and subsequent oxidative stress. Additionally, hypoxanthine analogs have applications in research related to cellular responses to hypoxia. -
Purine Nucleoside Analog
N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound targets indolent lymphoid malignancies through mechanisms such as inhibition of DNA synthesis and induction of apoptosis. It is a valuable reagent for cancer research, enabling the investigation of nucleotide-related pathways and therapeutic approaches in oncology. -
Purine Nucleoside Analog
5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological effects are primarily mediated through the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development strategies. -
Uridine Analog
1-(2,3,5-Tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione is a uridine analog that targets nucleoside pathways. This compound exhibits potential antiepileptic properties and is suitable for investigating anticonvulsant and anxiolytic activities. Additionally, it holds promise for the development of novel agents aimed at managing hypertension. -
Adenosine Analog
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenosine analog that primarily acts as a smooth muscle vasodilator. This compound has demonstrated potential in inhibiting cancer progression, making it valuable for cancer research. It serves as a useful tool in studies focused on adenosine receptor modulation and vascular biology. -
Nucleoside Metabolite
1,2-Dihydroxy-5-(methylthio)-1-penten-3-one is a nucleoside metabolite known for its role in various biochemical pathways. This compound exhibits significant biological activity, contributing to studies focused on nucleotide metabolism and cellular signaling. It serves as a valuable tool in research applications aimed at understanding nucleoside dynamics and their implications in cellular processes. -
Purine Nucleoside Analog
N6-Furfuryl-2’-C-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable reagent for cancer research and therapeutic development. This compound is utilized in studies focused on nucleoside analogs and their potential applications in oncology. -
Nucleoside Metabolite
L-Dopachrome is a nucleoside metabolite that plays a critical role in the biosynthesis and metabolism of melanin. It serves as an intermediate in the enzymatic conversion of L-DOPA to eumelanin and has been studied for its effects on pigmentation processes and potential implications in neurological health. This compound is valuable for research applications related to melanin synthesis, skin biology, and neurodegenerative conditions. -
Antitumor Agent
Flurocitabine hydrochloride is an antitumor agent that exerts its effects by undergoing hydrolysis in vivo to yield two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). These metabolites are involved in disrupting nucleic acid synthesis, making Flurocitabine hydrochloride a valuable tool in cancer research. Its ability to target tumor growth positions it as a significant compound for studies focused on chemotherapy and the development of novel anticancer therapies. -
Purine Nucleoside Analog
5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is essential for studying the effects of nucleoside analogs in oncological applications. -
Purine Nucleoside Analog
2'-C-Ethynyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis. Additionally, 2'-C-Ethynyluridine serves as a click chemistry reagent due to its alkyne group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This dual functionality makes it a valuable tool in chemical biology and therapeutic research. -
Adenosine Analog
3’-O-Propargyladenosine is an adenosine analog that primarily targets adenosine receptors, acting as a vasodilator and exhibiting potential anti-cancer properties. It serves as a valuable tool in research applications involving click chemistry, due to its alkyne functional group, which facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This compound is instrumental in the study of biochemical pathways and therapeutic interventions related to adenosine signaling and vascular biology. -
Purine Nucleoside Analog
3'-Azido-3'-deoxy-beta-L-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in treating indolent lymphoid malignancies. Its mechanism of action includes the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound acts as a versatile click chemistry reagent, featuring an azide group capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-containing molecules, making it useful for various biochemical applications. -
Nucleoside Metabolite
(2-Amino-1-hydroxyethyl)phosphonate, also known as 1-Hydroxy-2-aminoethylphosphonic acid, functions as a nucleoside metabolite. This compound plays a significant role in biochemical pathways associated with nucleotide metabolism and cell signaling. Its research applications include studies on metabolic processes, neuropharmacology, and the investigation of phosphonate derivatives in various biological systems. -
Purine Nucleoside Analog
7-(2-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine functions as a purine nucleoside analog. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through its ability to inhibit DNA synthesis and promote apoptosis. It is a valuable tool for research in cancer biology, particularly in studies focused on therapeutic strategies targeting nucleoside metabolism and cell proliferation. -
Thymidine Analog
2',3',5'-Tri-O-acetyl-5-cyanouridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound can serve as a valuable tool for labeling cells and monitoring DNA synthesis in various biological systems. Its utility in research makes it ideal for studies involving DNA replication and cell proliferation. -
Purine Nucleoside Analog
N6-iso-Propyl-2’-O-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its biological mechanism involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research and therapeutic studies. This compound is instrumental for researchers investigating novel treatments for hematologic cancers and exploring the molecular pathways associated with nucleoside analogs. -
Purine Nucleoside Analog
3'-O-DMTr-thymidine 5'-CE phosphoramidite is a purine nucleoside analog designed for nucleic acid synthesis and incorporation into oligonucleotides. It exhibits significant biological activity by inhibiting DNA synthesis and facilitating apoptosis, making it valuable in research focused on antitumor therapies. This compound is particularly relevant for exploring novel treatments for indolent lymphoid malignancies. -
Purine Nucleoside Analog
3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog that demonstrates potent antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valued in oncological research for its potential to elucidate mechanisms of tumorigenesis and therapeutics. -
Purine Nucleoside Analog
Alpha-5-Methyluridine is a purine nucleoside analog that exhibits notable antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to cell cycle disruption and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Adenosine Analog
N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenosine analog that primarily targets adenosine receptors. It exhibits biological activities such as smooth muscle relaxation and has demonstrated potential in inhibiting cancer progression. This compound is useful in various research applications, particularly in the development of nucleic acid-based therapeutics and the study of adenosine receptor signaling pathways.
