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9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine

Purine Nucleoside Analog

9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine is a purine nucleoside analog that inhibits DNA synthesis. This compound exhibits significant antitumor activity against indolent lymphoid malignancies, with mechanisms that include the induction of apoptosis. It serves as a valuable tool in cancer research for understanding the effects of nucleoside modifications on tumor progression and treatment response.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2072145-40-3
Applications	Purine Nucleoside Analog
Formula	C₂₀H₁₈Cl₂N₄O₆
Molecular Weight	481.29
SMILES	CO[C@H]1[C@@H](OC(C)=O)[C@H](N(C=N2)C3=C2C(Cl)=NC(Cl)=N3)O[C@@H]1COC(C4=CC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.