E 2012

Catalog No.: A11393

gamma-secretase modulator

E 2012

E 2012 Chemical Structure

CAS NO. 870843-42-8

E 2012 is γ-secretase inhibitor.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$135.00
25 mg
$220.00
50 mg
$350.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yesuvadian R, .et al. Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: a high-resolution NMR study., Biochem Biophys Res Commun., 2014, May 16;447(4):590-5 PMID: 24747079

Biological Activity

E 2012 is γ-secretase inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.19 mL 238.38 mL
0.5 mM 4.77 mL 23.84 mL 47.68 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11393
Actions Modulator
M. Wt 419.49
Formula C25H26FN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870843-42-8
Synonyms E-2012,E2012
SMILES CC1=CN(C=N1)C2=C(C=C(C=C2)/C=C/3\CCCN(C3=O)[[email protected]@H](C)C4=CC=C(C=C4)F)OC

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