Epoxyquinomicin A is an antibiotic derived from the bacterium Amycolatopsis sp., exhibiting significant antimicrobial activity against various pathogens including Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with minimum inhibitory concentrations (MIC) ranging from 3 to 12.5 µg/mL. Additionally, Epoxyquinomicin A demonstrates cytotoxic effects on cancer cell lines such as L1210, B16, and S180, with IC50 values between 2 and 8 µg/mL. Its anti-inflammatory properties have also been noted, particularly in models of collagen-induced arthritis, making it a valuable reagent for research in microbiology and oncology.
Epoxyquinomicin A is an antibiotic derived from the bacterium Amycolatopsis sp., exhibiting significant antimicrobial activity against various pathogens including Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with minimum inhibitory concentrations (MIC) ranging from 3 to 12.5 µg/mL. Additionally, Epoxyquinomicin A demonstrates cytotoxic effects on cancer cell lines such as L1210, B16, and S180, with IC50 values between 2 and 8 µg/mL. Its anti-inflammatory properties have also been noted, particularly in models of collagen-induced arthritis, making it a valuable reagent for research in microbiology and oncology.
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