Etoricoxib D4

Catalog No.: A21877

COX-2 inhibitor

Etoricoxib D4

Etoricoxib D4 Chemical Structure

CAS NO. 1131345-14-6

Etoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.

Availability: In stock

Package Price Qty
1 mg
$162.00
5 mg
$486.00
10 mg
$828.00
50 mg
$2,484.00
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Biological Activity

Etoricoxib D4 (MK-0663 D4) is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.56 mL 137.79 mL 275.58 mL
0.5 mM 5.51 mL 27.56 mL 55.12 mL
1 mM 2.76 mL 13.78 mL 27.56 mL
5 mM 0.55 mL 2.76 mL 5.51 mL

*The above data is based on the productmolecular weight 362.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21877
Actions Inhibitor
CAS No. 1131345-14-6
Formula C18H11D4ClN2O2S
M. Wt 362.87
Purity >98%
Synonyms MK-0663 D4; L-791456 D4
SMILES ClC(C=N1)=CC(C2=C([2H])C([2H])=C(S(C)(=O)=O)C([2H])=C2[2H])=C1C3=CN=C(C)C=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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