Etoricoxib

Catalog No.: A13770

COX-2 inhibitor

Etoricoxib Chemical Structure

CAS NO. 202409-33-4

Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

Availability: In stock

Package Price Qty
10 mg
$55.00
25 mg
$90.00
50 mg
$110.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
Targets
COX-2
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.87 mL 139.34 mL 278.68 mL
0.5 mM 5.57 mL 27.87 mL 55.74 mL
1 mM 2.79 mL 13.93 mL 27.87 mL
5 mM 0.56 mL 2.79 mL 5.57 mL

*The above data is based on the productmolecular weight 358.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13770
Actions Inhibitor
M. Wt 358.84
Formula C18H15ClN2O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 202409-33-4
Synonyms Arcoxia, MK-663, MK-0663
SMILES CC1=NC=C(C=C1)C2=NC=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)Cl

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