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Etoricoxib

COX-2 inhibitor

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Catalog No. A13770

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Etoricoxib 10mg A13770-10
$110.00
Etoricoxib 25mg A13770-25
$240.00
Etoricoxib 50mg A13770-50
$420.00
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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

Etoricoxib

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Chemical Information

Catalog Num A13770
Actions Inhibitor
M. Wt 358.84
Formula C18H15ClN2O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 202409-33-4
Synonyms Arcoxia, MK-663, MK-0663
SMILES CC1=NC=C(C=C1)C2=NC=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)Cl

Biological Activity

Description
Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
Targets
COX-2

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.87 mL 139.34 mL 278.68mL
0.5 mM 5.57 mL 27.87 mL 55.74 mL
1 mM 2.79 mL 13.93 mL 27.87 mL
5 mM 0.56 mL 2.79 mL 5.57 mL

*The above data is based on the productmolecular weight 358.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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